PHB and LONRF3

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		PHB	LONRF3
Gene Name		prohibitin	LON peptidase N-terminal domain and ring finger 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding	ATP-dependent Peptidase Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Histone Deacetylation Negative Regulation Of Cell Growth Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Progesterone Receptor Signaling Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Interleukin-6 DNA Biosynthetic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Proteolysis
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 19430483) Prostate cancer ( 23535732)
Protein-Protein Interactions		19 interactors: ANXA2 COX6C E2F1 ESR1 HDAC1 LONRF3 MAP3K10 NAP1L1 NCOR1 RAF1 RB1 RBL1 RBL2 SIN3A SMARCA2 SMARCA4 SUMO4 TP53 XPO1	4 interactors: APPBP2 NOTCH2NL PHB SMURF1
Entrez ID		5245	79836
HPRD ID		01454	06708
Ensembl ID		ENSG00000167085	ENSG00000175556
Uniprot IDs		A8K401 B4DY47 P35232 Q53FV0	Q496Y0
PDB IDs		1LU7
Enriched GO Terms of Interacting Partners?		Chromatin Organization Negative Regulation Of Gene Expression Chromosome Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Chromatin Remodeling Transcription, DNA-templated Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Transcription, DNA-templated Response To Transforming Growth Factor Beta RNA Biosynthetic Process Regulation Of Fibroblast Proliferation Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Aortic Smooth Muscle Cell Differentiation Regulation Of Cell Proliferation Regulation Of Cell Cycle Phase Transition Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Positive Regulation Of Gene Expression Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Cycle Process Gene Expression Negative Regulation Of Signaling Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Phosphorylation Rhythmic Process
Tagcloud ?		bacterium briefly cloned comamonas deduced degrading depolymerase depolymerases distinguished encodes exfoliatus gram homologies homology hydrolysis hydrolyze hydroxyalkanoate hydroxybutyrate hydroxyoctanoate isolate k10 pha phaz pho poly sp streptomyces subgroup utilize
Tagcloud (Difference) ?		bacterium briefly cloned comamonas deduced degrading depolymerase depolymerases distinguished encodes exfoliatus gram homologies homology hydrolysis hydrolyze hydroxyalkanoate hydroxybutyrate hydroxyoctanoate isolate k10 pha phaz pho poly sp streptomyces subgroup utilize
Tagcloud (Intersection) ?