LARS and EEF1G

Number of citations of the paper that reports this interaction (PMID 11829477)
11

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		LARS	EEF1G
Gene Name		leucyl-tRNA synthetase	eukaryotic translation elongation factor 1 gamma
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	Aminoacyl-tRNA Editing Activity Leucine-tRNA Ligase Activity Methionine-tRNA Ligase Activity Protein Binding ATP Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Leucyl-tRNA Aminoacylation Methionyl-tRNA Aminoacylation Regulation Of Translational Fidelity Gene Expression	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Translation Eukaryotic Translation Elongation
Drugs		L-Leucine
Diseases
GWAS
Protein-Protein Interactions		1 interactors: EEF1G	87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		51520	1937
HPRD ID		01042	11745
Ensembl ID		ENSG00000133706	ENSG00000254772
Uniprot IDs		B4DER1 B4DJ10 F5H698 Q9P2J5	P26641 Q53YD7
PDB IDs		2WFD	1PBU
Enriched GO Terms of Interacting Partners?			Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity
Tagcloud ?		5r 5rm 5rs airway airways allergen anchored asthma asthmatic asthmatics atopic bhr bronc bronchial committed corticosteroid eosinophil eosinophilia eosinophils episodic explant fev1 hyperresponsiveness immunocytochemical parasitic stats strengthened transduce transducers	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		5r 5rm 5rs airway airways allergen anchored asthma asthmatic asthmatics atopic bhr bronc bronchial committed corticosteroid eosinophil eosinophilia eosinophils episodic explant fev1 hyperresponsiveness immunocytochemical parasitic stats strengthened transduce transducers	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?