ZNF107 and HIPK3

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF107	HIPK3
Gene Name		zinc finger protein 107	homeodomain interacting protein kinase 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus	Nucleus Cytoplasm PML Body
	Molecular Function	Molecular_function DNA Binding Metal Ion Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Biological_process	Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: HIPK3 SMAD7	36 interactors: AR ARRB2 C1QA CREB1 DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I ZNF107 ZYX
Entrez ID		51427	10114
HPRD ID		18669	05111
Ensembl ID		ENSG00000196247	ENSG00000110422
Uniprot IDs		Q8WVL4 Q9UII5	Q9H422
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Phosphorylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of JUN Kinase Activity Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Cellular Protein Complex Localization MRNA Transcription Response To Laminar Fluid Shear Stress Negative Regulation Of Protein Metabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Protein Complex Localization Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Activin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Signaling Ventricular Septum Morphogenesis Negative Regulation Of JNK Cascade Negative Regulation Of Stem Cell Differentiation Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Membrane Depolarization Response To Fluid Shear Stress Regulation Of Phosphorylation Protein Phosphorylation Negative Regulation Of BMP Signaling Pathway Ventricular Cardiac Muscle Tissue Morphogenesis Peptidyl-threonine Phosphorylation Adherens Junction Assembly Regulation Of Phosphorus Metabolic Process Ventricular Cardiac Muscle Tissue Development Ventricular Septum Development Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cardiac Muscle Tissue Morphogenesis Artery Morphogenesis Cardiac Septum Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Muscle Tissue Morphogenesis Negative Regulation Of Ubiquitin-protein Transferase Activity Artery Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Proteasomal Protein Catabolic Process	Regulation Of Signaling Regulation Of Signal Transduction Regulation Of RNA Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Negative Regulation Of Gene Expression Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Signal Transduction Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Motor Neuron Apoptotic Process Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Protein Oligomerization RNA Biosynthetic Process Response To Organic Substance Cellular Response To Organic Substance RNA Splicing Regulation Of Extrinsic Apoptotic Signaling Pathway Viral Process Regulation Of RNA Splicing Cellular Metabolic Process RNA Processing Cellular Response To Growth Factor Stimulus Androgen Receptor Signaling Pathway Response To Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Signaling Necroptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
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