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HIPK3 and ZNF107
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HIPK3
ZNF107
Gene Name
homeodomain interacting protein kinase 3
zinc finger protein 107
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
PML Body
Cellular_component
Nucleus
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
ATP Binding
Molecular_function
DNA Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Apoptotic Process
MRNA Transcription
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Biological_process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
36 interactors:
AR
ARRB2
C1QA
CREB1
DAXX
FADD
FAS
FLNC
GLUL
GORASP1
GRB2
HEYL
HNRNPA1
HNRNPA2B1
HNRNPH1
LIMD1
LIMK2
LIMS2
MBD1
MTMR4
NR2F2
RGS3
SIAH1
SIAH2
SKIL
SNIP1
SRSF1
SRSF5
SUMO1
TGFB1I1
TOX4
TP73
TRA2B
UBE2I
ZNF107
ZYX
2 interactors:
HIPK3
SMAD7
Entrez ID
10114
51427
HPRD ID
05111
18669
Ensembl ID
ENSG00000110422
ENSG00000196247
Uniprot IDs
Q9H422
Q8WVL4
Q9UII5
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Motor Neuron Apoptotic Process
Transcription, DNA-templated
Cellular Aromatic Compound Metabolic Process
Protein Oligomerization
RNA Biosynthetic Process
Response To Organic Substance
Cellular Response To Organic Substance
RNA Splicing
Regulation Of Extrinsic Apoptotic Signaling Pathway
Viral Process
Regulation Of RNA Splicing
Cellular Metabolic Process
RNA Processing
Cellular Response To Growth Factor Stimulus
Androgen Receptor Signaling Pathway
Response To Growth Factor
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Signaling
Necroptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Transferase Activity
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Phosphorylation
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Negative Regulation Of Transcription By Competitive Promoter Binding
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of JUN Kinase Activity
Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Catalytic Activity
Negative Regulation Of Cellular Protein Metabolic Process
Cellular Protein Complex Localization
MRNA Transcription
Response To Laminar Fluid Shear Stress
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Peptidyl-threonine Phosphorylation
Protein Complex Localization
Negative Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Activin Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
Negative Regulation Of Signal Transduction
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Signaling
Ventricular Septum Morphogenesis
Negative Regulation Of JNK Cascade
Negative Regulation Of Stem Cell Differentiation
Negative Regulation Of Stress-activated MAPK Cascade
Regulation Of Membrane Depolarization
Response To Fluid Shear Stress
Regulation Of Phosphorylation
Protein Phosphorylation
Negative Regulation Of BMP Signaling Pathway
Ventricular Cardiac Muscle Tissue Morphogenesis
Peptidyl-threonine Phosphorylation
Adherens Junction Assembly
Regulation Of Phosphorus Metabolic Process
Ventricular Cardiac Muscle Tissue Development
Ventricular Septum Development
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Cardiac Muscle Tissue Morphogenesis
Artery Morphogenesis
Cardiac Septum Morphogenesis
Regulation Of Epithelial To Mesenchymal Transition
Muscle Tissue Morphogenesis
Negative Regulation Of Ubiquitin-protein Transferase Activity
Artery Development
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Proteasomal Protein Catabolic Process
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