NPPB and KRTAP10-9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NPPB	KRTAP10-9
Gene Name		natriuretic peptide B	keratin associated protein 10-9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Protein Complex	Keratin Filament
	Molecular Function	Receptor Binding Hormone Activity Diuretic Hormone Activity
	Biological Process	CGMP Biosynthetic Process Cell Surface Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway Body Fluid Secretion Regulation Of Blood Pressure Negative Regulation Of Angiogenesis Negative Regulation Of Cell Growth Positive Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Regulation Of Vasodilation Regulation Of Vascular Permeability Regulation Of Blood Vessel Size
Pathways
Drugs		Carvedilol
Diseases
GWAS		Blood pressure ( 21909110) Systolic blood pressure ( 19430483)
Protein-Protein Interactions		10 interactors: EWSR1 HDAC4 KRT40 KRTAP10-3 KRTAP10-9 NOTCH2NL NPR1 NPR2 NPR3 PSMA3	163 interactors: ADAMTSL4 AES ALDH3B1 ALPI ARFGAP1 ATXN7L1 AVPI1 BCL6B C10orf62 C11orf87 C16orf59 C19orf57 C19orf66 C5orf60 C9orf9 CARKD CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 DHX57 DMRT3 DOCK2 EIF4E2 FAM124B FAM161A FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 HBG1 HBZ HCK HOXA1 HOXB9 HPCAL1 HSD3B7 IGSF8 INPP5D IQUB ITGB5 KAT5 KIF9 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LUZP4 MAB21L3 MAPKBP1 MED30 MEOX2 MOBP MT1DP MXI1 NOTCH2NL NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PGAP2 PGLS PIN1 PLSCR1 PRKAB2 PRPF31 PTGER3 PVR PVRL3 RAB7A RHNO1 RSPO2 SCARB1 SCNM1 SLC23A1 SLC6A20 SMARCE1 SMCP SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TGOLN2 THAP10 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 WNT11 WT1-AS XCL2 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF20 ZNF264 ZNF317 ZNF417 ZNF439 ZNF440 ZNF473 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF697 ZNF699 ZNF792 ZNF844 ZSCAN21 ZSCAN26
Entrez ID		4879	386676
HPRD ID		08974	11195
Ensembl ID		ENSG00000120937	ENSG00000221837
Uniprot IDs		P16860	P60411
PDB IDs		1YK1 3N56
Enriched GO Terms of Interacting Partners?		Receptor Guanylyl Cyclase Signaling Pathway Positive Regulation Of Urine Volume CGMP Biosynthetic Process Regulation Of Blood Pressure CGMP Metabolic Process Intracellular Signal Transduction Cyclic Purine Nucleotide Metabolic Process Negative Regulation Of Smooth Muscle Cell Proliferation Blood Circulation Cyclic Nucleotide Biosynthetic Process Cyclic Nucleotide Metabolic Process Renal System Process Regulation Of Smooth Muscle Cell Proliferation Body Fluid Secretion Skeletal System Development Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Oocyte Maturation Signaling Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Cell Communication Negative Regulation Of Oocyte Development Osteoclast Proliferation Pancreatic Juice Secretion Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Cellular Response To Stimulus Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Ossification Response To Inactivity Ribonucleotide Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Negative Regulation Of Myotube Differentiation Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Protein Sumoylation Positive Regulation Of CGMP Biosynthetic Process Regulation Of Skeletal Muscle Fiber Development Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of CGMP Metabolic Process Regulation Of Protein Sumoylation Negative Regulation Of Striated Muscle Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Regulation Of Renal Sodium Excretion	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Keratinocyte Differentiation Cellular Metabolic Process Epidermis Development Epidermal Cell Differentiation Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phagocytosis Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Podosome Assembly Apoptotic Cell Clearance Penetration Of Zona Pellucida Organelle Disassembly Tissue Development Skin Development Epithelium Development Multicellular Organismal Development Bud Elongation Involved In Lung Branching Cellular Response To Lipid Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Inner Ear Morphogenesis Fertilization Negative Regulation Of ERBB Signaling Pathway Phagocytosis Anatomical Structure Development
Tagcloud ?		0x10 18x10 75x10 americans ancestry architecture arr blacks bnp cardioprotective checked cogent consortium copies directions dosages echogen gwa imputed klkb1 logarithmically lvm motivate natriuretic relations residuals rs198389 rs3733402 whites
Tagcloud (Difference) ?		0x10 18x10 75x10 americans ancestry architecture arr blacks bnp cardioprotective checked cogent consortium copies directions dosages echogen gwa imputed klkb1 logarithmically lvm motivate natriuretic relations residuals rs198389 rs3733402 whites
Tagcloud (Intersection) ?