MEP1A and VIP

Number of citations of the paper that reports this interaction (PMID 11278902)
30

Data Source:
BioGRID (enzymatic study)

		MEP1A	VIP
Gene Name		meprin A, alpha (PABA peptide hydrolase)	vasoactive intestinal peptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Meprin A Complex Extracellular Vesicular Exosome	Extracellular Region Neuronal Cell Body
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding
	Biological Process	Proteolysis Digestion	Positive Regulation Of Endothelial Cell Proliferation G-protein Coupled Receptor Signaling Pathway Body Fluid Secretion Learning Or Memory Positive Regulation Of Cell Proliferation Regulation Of Signal Transduction Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Vasodilation MRNA Stabilization Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Sensory Perception Of Pain Positive Regulation Of Penile Erection Prolactin Secretion
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AGT BDKRB1 CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP	8 interactors: MEOX2 MEP1A MME PRICKLE1 SGTA UBQLN4 VIPR1 VIPR2
Entrez ID		4224	7432
HPRD ID		02666	15950
Ensembl ID		ENSG00000112818	ENSG00000146469
Uniprot IDs		B7ZL91 Q16819	P01282
PDB IDs			2RRH 2RRI
Enriched GO Terms of Interacting Partners?		Response To Stimulus Blood Circulation G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Renal Sodium Excretion Regulation Of Ion Homeostasis Behavior Regulation Of Blood Pressure Cell Surface Receptor Signaling Pathway Regulation Of Renal Sodium Excretion Regulation Of Appetite Neuropeptide Signaling Pathway Regulation Of Excretion Feeding Behavior Signal Transduction Regulation Of Corticosterone Secretion Cell-cell Signaling Response To External Stimulus Regulation Of Cell Migration Signaling Regulation Of Cell Motility Secretion Cell Communication Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Locomotion Regulation Of Cellular Component Movement Cellular Homeostasis Regulation Of Neurological System Process Cellular Metal Ion Homeostasis Positive Regulation Of Transport Inflammatory Response Positive Regulation Of CAMP Biosynthetic Process Response To Nutrient Levels Cellular Cation Homeostasis Positive Regulation Of CAMP Metabolic Process Cellular Ion Homeostasis Single-organism Behavior Platelet Degranulation Response To Extracellular Stimulus Metal Ion Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Secretion By Cell Chemical Homeostasis Cellular Response To Stimulus Blood Vessel Development Regulation Of Cellular Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process	Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Digestion Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV-A Creatinine Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Somite Specification Response To UV-A Negative Regulation Of Cardiac Muscle Cell Differentiation Cellular Response To UV-B
Tagcloud ?		accumulating anthropometric borderline carriers disturbances exonuclease fertility fluorogenic genbank gg gt hirsutism homa homeostatic hormonal hyperandrogenemia id obese ovary overweight pcos polycystic prominent rs17468190 taqman triglyceride tt utr variants	acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine
Tagcloud (Difference) ?		accumulating anthropometric borderline carriers disturbances exonuclease fertility fluorogenic genbank gg gt hirsutism homa homeostatic hormonal hyperandrogenemia id obese ovary overweight pcos polycystic prominent rs17468190 taqman triglyceride tt utr variants	acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine
Tagcloud (Intersection) ?