LMNA and DUSP13

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LMNA	DUSP13
Gene Name		lamin A/C	dual specificity phosphatase 13
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Lamin Filament Nuclear Lamina Nucleoplasm Cytoplasm Cytosol Intermediate Filament Nuclear Speck Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Mitotic Cell Cycle Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Muscle Organ Development Regulation Of Cell Migration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Endoplasmic Reticulum Unfolded Protein Response Protein Localization To Nucleus Sterol Regulatory Element Binding Protein Import Into Nucleus Cellular Protein Metabolic Process Ventricular Cardiac Muscle Cell Development Cellular Response To Hypoxia Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Cell Aging Regulation Of Protein Localization To Nucleus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein Dephosphorylation Meiotic Nuclear Division Spermatogenesis Peptidyl-tyrosine Dephosphorylation
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: ACTB ALOX12 ALOX12B CASP1 CASP6 CDK1 DBNL DUSP13 EGF EMD FLNA FOS GZMA GZMB KAT5 KRTAP10-3 KRTAP10-7 LMNB1 MLIP MRPS26 NARF PCBP1 PCGF2 PRKCA RB1 RBBP4 SH3KBP1 SMAD3 SREBF1 STAC SUMO4 SVIL SYNE1 TMPO TOR1A TOR1AIP1 UBE2I UCHL5 UNC13D URB2 VAV1 YWHAQ ZNF239	8 interactors: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 LMNA SMURF1 TGFBR1
Entrez ID		4000	51207
HPRD ID		01035	13251
Ensembl ID		ENSG00000160789	ENSG00000079393
Uniprot IDs		P02545	F2Z2C4 Q6B8I1 Q9UII6 U3KQ82 U3KQE1
PDB IDs		1IFR 1IVT 1X8Y 2XV5 2YPT 3GEF 3V4Q 3V4W 3V5B	2GWO 2PQ5
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Transport Nucleus Organization Nuclear Envelope Organization Regulation Of Signaling Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Organelle Organization Positive Regulation Of Nucleocytoplasmic Transport Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Cellular Response To Growth Factor Stimulus Positive Regulation Of Signal Transduction Response To Growth Factor Immune Response Cellular Response To Organic Substance Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Transport Regulation Of Catenin Import Into Nucleus Epidermal Growth Factor Receptor Signaling Pathway Execution Phase Of Apoptosis ERBB Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Protein Import Into Nucleus Positive Regulation Of Cellular Protein Metabolic Process Organ Development Cellular Response To Stimulus Response To Wounding Platelet Activation Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Regulation Of Nucleocytoplasmic Transport Immune System Process Nuclear Membrane Organization Mitotic Nuclear Envelope Disassembly Intracellular Signal Transduction Positive Regulation Of Protein Localization To Nucleus Hepoxilin Metabolic Process Hepoxilin Biosynthetic Process	Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Pharyngeal System Development Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Extrinsic Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Phosphorylation Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction BMP Signaling Pathway Sterol Regulatory Element Binding Protein Import Into Nucleus Endocardial Cushion Cell Fate Commitment Negative Regulation Of Signaling Heart Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Organic Substance Cardiac Muscle Cell Differentiation Mesenchymal Cell Development Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Cellular Response To Growth Factor Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Growth Factor Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Phosphorus Metabolic Process Mesenchymal Cell Differentiation Cardiocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Gene Expression Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Cytoplasmic Transport Positive Regulation Of Protein Phosphorylation Regulation Of Gene Expression Regulation Of Signaling
Tagcloud ?		1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Difference) ?		1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Intersection) ?