LGALS1 and CD7

Number of citations of the paper that reports this interaction (PMID 10490978)
48

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		LGALS1	CD7
Gene Name		lectin, galactoside-binding, soluble, 1	CD7 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Intracellular Nucleus Cytoplasm Cell Surface Extracellular Matrix Extracellular Vesicular Exosome	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding Signal Transducer Activity Protein Binding Galactoside Binding Lactose Binding Protein Homodimerization Activity Laminin Binding Poly(A) RNA Binding	Receptor Activity
	Biological Process	Plasma Cell Differentiation Apoptotic Process Signal Transduction Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Multicellular Organismal Response To Stress Positive Regulation Of Erythrocyte Aggregation Response To Drug Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Myoblast Differentiation Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound	Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway T Cell Activation Homeostasis Of Number Of Cells Within A Tissue
Pathways
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		14 interactors: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS ITGB1 LGALS3BP MUC16 PTPRC SPN USP4 VPREB1	8 interactors: CPTP CTSL LGALS1 NFKBIA PI4KA PIK3R1 SECTM1 SNAP29
Entrez ID		3956	924
HPRD ID		01040	01732
Ensembl ID		ENSG00000100097	ENSG00000173762
Uniprot IDs		P09382	P09564 Q29VG3
PDB IDs		1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Leukocyte Cell-cell Adhesion Lymphocyte Activation Leukocyte Activation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Homotypic Cell-cell Adhesion Leukocyte Differentiation Cell Activation Regulation Of Immune System Process Leukocyte Migration Defense Response Regulation Of Immune Response Lymphocyte Differentiation Heterotypic Cell-cell Adhesion Immune System Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell Adhesion Hemopoiesis Immune System Development Positive Regulation Of Cell Adhesion Positive Regulation Of Protein Phosphorylation Regulation Of Cell-cell Adhesion T Cell Differentiation Regulation Of Lymphocyte Activation Locomotion T Cell Selection Blood Coagulation Positive Regulation Of Intracellular Signal Transduction Hemostasis Cell Migration Positive Regulation Of Phosphorylation Cellular Defense Response Regulation Of Cell Activation Visual Learning Positive Regulation Of T Cell Activation Cell Motility Positive Regulation Of Protein Modification Process Visual Behavior Positive Regulation Of Homotypic Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion T Cell Costimulation Regulation Of Body Fluid Levels Associative Learning Regulation Of Protein Phosphorylation	Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Immune System Process Apoptotic Process Programmed Cell Death Cell Death Death Signaling Immune System Process Cellular Glucose Homeostasis T Cell Costimulation Cell Communication Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Erythrocyte Aggregation NFAT Protein Import Into Nucleus Ceramide 1-phosphate Transport Phosphatidylinositol Phosphorylation Immune Response-regulating Signaling Pathway Regulation Of Transcription Factor Import Into Nucleus Lipid Phosphorylation B Cell Differentiation Regulation Of Immune System Process Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Transcription Factor Import Into Nucleus Macrophage Apoptotic Process Protein Import Into Nucleus Phosphatidylinositol Biosynthetic Process Nuclear Import Cellular Response To Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Phosphatidylinositol-mediated Signaling Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Activation Of Innate Immune Response Protein Import B Cell Activation Ceramide Transport Protein Localization To Nucleus Regulation Of Protein Import Into Nucleus Negative Regulation Of Cell Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Innate Immune Response Regulation Of Cell-substrate Adhesion Regulation Of Protein Localization To Nucleus
Tagcloud ?		abundance adenocarcinomas aversely clues die dismal ductal extend galectin lethal pancreas pancreatic pdac personalized prelp prolargin proteome proteomes rarely rps8 s8 sts survive survivors tgfbeta top upstream vegfa vlts	abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations thy1 trisomy
Tagcloud (Difference) ?		abundance adenocarcinomas aversely clues die dismal ductal extend galectin lethal pancreas pancreatic pdac personalized prelp prolargin proteome proteomes rarely rps8 s8 sts survive survivors tgfbeta top upstream vegfa vlts	abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations thy1 trisomy
Tagcloud (Intersection) ?