KPNA5 and SPOPL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KPNA5	SPOPL
Gene Name		karyopherin alpha 5 (importin alpha 6)	speckle-type POZ protein-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Transporter Activity
	Biological Process	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway	Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes	Hedgehog 'on' state Signaling by Hedgehog
Drugs
Diseases
GWAS		Telomere length ( 21460395)	Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		7 interactors: ANP32A ANP32B BRMS1 CDKN1B IL32 NUP50 SPOPL	1 interactors: KPNA5
Entrez ID		3841	339745
HPRD ID		05179	11261
Ensembl ID		ENSG00000196911	ENSG00000144228
Uniprot IDs		O15131	Q6IQ16
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Anoikis Inner Ear Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Autophagic Cell Death Ear Development Regulation Of Protein Metabolic Process Protein Processing Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus	NLS-bearing Protein Import Into Nucleus Protein Import Into Nucleus Nuclear Import Protein Import Protein Localization To Nucleus
Tagcloud ?		accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Difference) ?		accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Intersection) ?