SPOPL and KPNA5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPOPL	KPNA5
Gene Name		speckle-type POZ protein-like	karyopherin alpha 5 (importin alpha 6)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function		Protein Binding Protein Transporter Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway
Pathways		Hedgehog 'on' state Signaling by Hedgehog	ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Response to antipsychotic treatment ( 23241943)	Telomere length ( 21460395)
Protein-Protein Interactions		1 interactors: KPNA5	7 interactors: ANP32A ANP32B BRMS1 CDKN1B IL32 NUP50 SPOPL
Entrez ID		339745	3841
HPRD ID		11261	05179
Ensembl ID		ENSG00000144228	ENSG00000196911
Uniprot IDs		Q6IQ16	O15131
PDB IDs
Enriched GO Terms of Interacting Partners?		NLS-bearing Protein Import Into Nucleus Protein Import Into Nucleus Nuclear Import Protein Import Protein Localization To Nucleus	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Anoikis Inner Ear Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Autophagic Cell Death Ear Development Regulation Of Protein Metabolic Process Protein Processing Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus
Tagcloud ?			accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Difference) ?			accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Intersection) ?