KPNA5 and IL32

Number of citations of the paper that reports this interaction (PMID 25178676)
0

Data Source:
BioGRID (two hybrid)

		KPNA5	IL32
Gene Name		karyopherin alpha 5 (importin alpha 6)	interleukin 32
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Extracellular Space Membrane
	Molecular Function	Protein Binding Protein Transporter Activity	Cytokine Activity Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway	Defense Response Immune Response Cell Adhesion
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Telomere length ( 21460395)	HIV-1 susceptibility ( 22174851)
Protein-Protein Interactions		7 interactors: ANP32A ANP32B BRMS1 CDKN1B IL32 NUP50 SPOPL	10 interactors: C1QB HSPA8 KPNA5 NDN NQO2 PRTN3 RPL4 SNRNP70 TUT1 ZFPM2
Entrez ID		3841	9235
HPRD ID		05179	09346
Ensembl ID		ENSG00000196911	ENSG00000008517
Uniprot IDs		O15131	C6GKH1 G3LU47 P24001
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Anoikis Inner Ear Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Autophagic Cell Death Ear Development Regulation Of Protein Metabolic Process Protein Processing Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus	Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Positive Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Fibril Organization Regulation Of MRNA Processing MRNA Processing Regulation Of RNA Splicing RNA Metabolic Process Right Ventricular Cardiac Muscle Tissue Morphogenesis Gene Expression Regulation Of Fibril Organization RNA Processing Negative Regulation Of Female Gonad Development Clathrin Coat Disassembly Cellular Protein Complex Disassembly Mature Conventional Dendritic Cell Differentiation Protein Complex Disassembly Gonadal Mesoderm Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development Negative Regulation Of Phagocytosis Nucleobase-containing Compound Metabolic Process
Tagcloud ?		accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial	attempt basal cancers candidate datasets define defining designated differential geo hyperplastic incredible luminal mb231 mcf7 mda microarrays omnibus past progesterone public publically search suitable tma tmas tnbc triple validation
Tagcloud (Difference) ?		accurately adam12 centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial	attempt basal datasets define defining designated differential geo hyperplastic incredible luminal mb231 mcf7 mda microarrays omnibus past progesterone public publically search suitable tma tmas tnbc triple validation
Tagcloud (Intersection) ?		cancers candidate