ARF5 and AP1B1

Number of citations of the paper that reports this interaction (PMID 11926829)
12

Data Source:
HPRD (in vitro, in vivo)

		ARF5	AP1B1
Gene Name		ADP-ribosylation factor 5	adaptor-related protein complex 1, beta 1 subunit
Image
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Transporter Activity Protein Binding Protein Transporter Activity Protein Kinase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways			Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS		Type 2 diabetes ( 23532257)	Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions		9 interactors: AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 GGA1 IKBKG PIP5K1A RAB11FIP3	22 interactors: AMPH AP1G1 AP1M1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A NTRK2 PIP5K1C PRKDC SHBG SMAD2
Entrez ID		381	162
HPRD ID		00055	02541
Ensembl ID		ENSG00000004059	ENSG00000100280
Uniprot IDs		A4D0Z3 P84085	Q10567
PDB IDs		2B6H	4HMY
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Cellular Localization Intracellular Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Vesicle-mediated Transport Ruffle Organization Establishment Of Protein Localization Protein Localization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Vesicle Localization Vesicle Localization	Post-Golgi Vesicle-mediated Transport Regulation Of Defense Response To Virus By Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Protein Localization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Organelle Organization Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Cellular Localization Viral Process Regulation Of Defense Response To Virus Establishment Of Vesicle Localization Melanosome Organization Pigment Granule Organization Vesicle Localization Cell Cycle Cell Cycle Checkpoint Antigen Processing And Presentation Of Peptide Antigen Cell Cycle Process Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Establishment Of Localization In Cell Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Antigen Processing And Presentation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Chromosome Segregation Negative Regulation Of Mitotic Cell Cycle Phase Transition Establishment Of Organelle Localization Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Cell Differentiation Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Checkpoint Negative Regulation Of Proteolysis Cellular Protein Localization Response To Gamma Radiation Negative Regulation Of Protein Processing Cellular Pigmentation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Temperature Stimulus Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Protein Processing Negative Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually
Tagcloud (Difference) ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually
Tagcloud (Intersection) ?