KCNJ9 and KCNJ6

Number of citations of the paper that reports this interaction (PMID 10956667)
23

Data Source:
HPRD (in vitro, in vivo)

		KCNJ9	KCNJ6
Gene Name		potassium channel, inwardly rectifying subfamily J, member 9	potassium channel, inwardly rectifying subfamily J, member 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity PDZ Domain Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Synaptic Transmission Potassium Ion Import Regulation Of Ion Transmembrane Transport	Potassium Ion Transport Synaptic Transmission Potassium Ion Import Regulation Of Ion Transmembrane Transport
Pathways		GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses	GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs			Halothane
Diseases
GWAS			Electroencephalographic traits in alcoholism ( 22554406)
Protein-Protein Interactions		5 interactors: ADRB2 DRD2 DRD4 KCNJ3 KCNJ6	7 interactors: ADRB2 BIRC5 DLG1 DRD2 GABBR1 KCNJ3 KCNJ9
Entrez ID		3765	3763
HPRD ID		02959	02929
Ensembl ID
Uniprot IDs		Q92806	P48051
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transport Regulation Of Adenylate Cyclase Activity Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Negative Regulation Of Voltage-gated Calcium Channel Activity Regulation Of CAMP Biosynthetic Process Regulation Of Ion Transmembrane Transport Regulation Of CAMP Metabolic Process Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Synaptic Transmission, Dopaminergic Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Response To Histamine Behavioral Response To Ethanol G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission, Dopaminergic Arachidonic Acid Secretion Behavioral Response To Cocaine Regulation Of Neurotransmitter Uptake Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Cation Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Potassium Ion Import Temperature Homeostasis Cell-cell Signaling Dopamine Metabolic Process Negative Regulation Of CAMP Biosynthetic Process Activation Of Protein Kinase Activity Negative Regulation Of CAMP Metabolic Process Dopamine Receptor Signaling Pathway Response To Amphetamine Response To Abiotic Stimulus Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Transporter Activity Long-chain Fatty Acid Transport Negative Regulation Of Calcium Ion Transport Catecholamine Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Blood Pressure Response To Cocaine Response To Amine Negative Regulation Of Transmembrane Transport Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Acid Secretion	Synaptic Transmission Regulation Of Ion Transport Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Cell-cell Signaling Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Peristalsis Regulation Of Ion Transmembrane Transport Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Potassium Ion Import Temperature Homeostasis Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Protein Kinase B Signaling Activation Of Protein Kinase Activity Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Blood Pressure Smooth Muscle Contraction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Potassium Ion Transport Regulation Of Catalytic Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Multicellular Organism Growth Positive Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase B Signaling Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Type B Pancreatic Cell Proliferation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Positive Regulation Of Cell Division Regulation Of Establishment Of Protein Localization Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Signaling Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cell Communication Negative Regulation Of Dopamine Secretion Positive Regulation Of Exit From Mitosis
Tagcloud ?			channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Difference) ?			channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Intersection) ?