KCNJ6 and KCNJ3

Number of citations of the paper that reports this interaction (PMID 9023358)
52

Data Source:
HPRD (in vivo, in vitro)

		KCNJ6	KCNJ3
Gene Name		potassium channel, inwardly rectifying subfamily J, member 6	potassium channel, inwardly rectifying subfamily J, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex External Side Of Plasma Membrane T-tubule
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Synaptic Transmission Potassium Ion Import Regulation Of Ion Transmembrane Transport	Potassium Ion Transport Synaptic Transmission Potassium Ion Import Regulation Of Ion Transmembrane Transport Response To Electrical Stimulus
Pathways		GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses	GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs		Halothane	Halothane
Diseases
GWAS		Electroencephalographic traits in alcoholism ( 22554406)
Protein-Protein Interactions		7 interactors: ADRB2 BIRC5 DLG1 DRD2 GABBR1 KCNJ3 KCNJ9	4 interactors: GNB1 KCNJ5 KCNJ6 KCNJ9
Entrez ID		3763	3760
HPRD ID		02929	03323
Ensembl ID			ENSG00000162989
Uniprot IDs		P48051	D2X9V0 D2XBF0 P48549
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Regulation Of Ion Transport Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Cell-cell Signaling Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Peristalsis Regulation Of Ion Transmembrane Transport Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Potassium Ion Import Temperature Homeostasis Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Protein Kinase B Signaling Activation Of Protein Kinase Activity Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Blood Pressure Smooth Muscle Contraction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Potassium Ion Transport Regulation Of Catalytic Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Multicellular Organism Growth Positive Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase B Signaling Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Type B Pancreatic Cell Proliferation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Positive Regulation Of Cell Division Regulation Of Establishment Of Protein Localization Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Signaling Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cell Communication Negative Regulation Of Dopamine Secretion Positive Regulation Of Exit From Mitosis	Potassium Ion Import Synaptic Transmission Potassium Ion Transmembrane Transport Cell-cell Signaling Potassium Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Monovalent Inorganic Cation Transport Metal Ion Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Cardiac Muscle Cell Apoptotic Process Muscle Cell Apoptotic Process Transmembrane Transport Ion Transport Cellular Response To Prostaglandin E Stimulus G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E Signaling Cell Communication Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Response To Catecholamine Stimulus Rhodopsin Mediated Signaling Pathway Dopamine Receptor Signaling Pathway Cellular Response To Glucagon Stimulus Cellular Response To Fatty Acid Response To Glucagon Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Sensory Perception Of Taste Response To Fatty Acid Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Detection Of Light Stimulus Cellular Response To Oxygen Levels
Tagcloud ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant	channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcna1 kcnd2 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant