IGKC and SMARCD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		IGKC	SMARCD1
Gene Name		immunoglobulin kappa constant	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Extracellular Vesicular Exosome Blood Microparticle	SWI/SNF Complex NpBAF Complex NBAF Complex
	Molecular Function	Antigen Binding	Transcription Coactivator Activity Protein Binding Protein Complex Scaffold
	Biological Process	Retina Homeostasis Receptor-mediated Endocytosis Immune Response Complement Activation Complement Activation, Classical Pathway Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Regulation Of Immune Response	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Chromatin-mediated Maintenance Of Transcription
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CD40LG IGHG1 MLH1 SMARCD1	44 interactors: ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CORO1A DPF3 EGFL7 ESR1 FEZ1 FOS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KRT15 KRT18 LDOC1 MED4 NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 SUV420H1 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		3514	6602
HPRD ID		00921	03438
Ensembl ID			ENSG00000066117
Uniprot IDs			Q96GM5
PDB IDs
Enriched GO Terms of Interacting Partners?		Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response Isotype Switching Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Immunoglobulin Production Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Leukocyte Activation Involved In Immune Response B Cell Activation Negative Regulation Of Mitotic Recombination DNA Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Immune Response Immunoglobulin Secretion Spindle Midzone Assembly Lymphocyte Activation Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Endothelial Cell Apoptotic Process Resolution Of Meiotic Recombination Intermediates Somatic Hypermutation Of Immunoglobulin Genes Leukocyte Activation Somatic Diversification Of Immune Receptors Via Somatic Mutation Regulation Of Immunoglobulin Secretion Nucleosome Disassembly Immune System Process Positive Regulation Of Gene Expression, Epigenetic Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Cell Activation Immune System Development Metaphase Plate Congression Regulation Of Endothelial Cell Apoptotic Process B Cell Proliferation Establishment Of Chromosome Localization Reciprocal Meiotic Recombination Positive Regulation Of Interleukin-12 Production Regulation Of Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Synapsis Mismatch Repair Homologous Chromosome Segregation	RNA Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Chromatin Organization Regulation Of Gene Expression Cellular Response To Organic Substance Response To Organic Substance Developmental Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter System Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Cell Death Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Multicellular Organismal Development DNA-templated Transcription, Initiation Hormone-mediated Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Hormone Stimulus Regulation Of Cellular Process Chromatin Modification
Tagcloud ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Difference) ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Intersection) ?