IGKC and IGHG1

Number of citations of the paper that reports this interaction (PMID 1522589)
3

Data Source:
HPRD (in vitro)

		IGKC	IGHG1
Gene Name		immunoglobulin kappa constant	immunoglobulin heavy constant gamma 1 (G1m marker)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Extracellular Vesicular Exosome Blood Microparticle	Extracellular Region Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Antigen Binding	Antigen Binding Protein Binding
	Biological Process	Retina Homeostasis Receptor-mediated Endocytosis Immune Response Complement Activation Complement Activation, Classical Pathway Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Regulation Of Immune Response	Complement Activation Complement Activation, Classical Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response
Pathways
Drugs
Diseases
GWAS			IgG levels ( 23225573)
Protein-Protein Interactions		4 interactors: CD40LG IGHG1 MLH1 SMARCD1	7 interactors: CD40LG FCGR3A FCGR3B IGKC SWAP70 TRIM21 UCHL5
Entrez ID		3514	3500
HPRD ID		00921	11755
Ensembl ID
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response Isotype Switching Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Immunoglobulin Production Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Leukocyte Activation Involved In Immune Response B Cell Activation Negative Regulation Of Mitotic Recombination DNA Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Immune Response Immunoglobulin Secretion Spindle Midzone Assembly Lymphocyte Activation Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Endothelial Cell Apoptotic Process Resolution Of Meiotic Recombination Intermediates Somatic Hypermutation Of Immunoglobulin Genes Leukocyte Activation Somatic Diversification Of Immune Receptors Via Somatic Mutation Regulation Of Immunoglobulin Secretion Nucleosome Disassembly Immune System Process Positive Regulation Of Gene Expression, Epigenetic Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Cell Activation Immune System Development Metaphase Plate Congression Regulation Of Endothelial Cell Apoptotic Process B Cell Proliferation Establishment Of Chromosome Localization Reciprocal Meiotic Recombination Positive Regulation Of Interleukin-12 Production Regulation Of Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Synapsis Mismatch Repair Homologous Chromosome Segregation	Immune Response Immune System Process Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Isotype Switching DNA Recombination Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Somatic Recombination Of Immunoglobulin Gene Segments Leukocyte Mediated Immunity Adaptive Immune Response Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Immunoglobulin Production Defense Response Response To Stimulus Negative Regulation Of Protein Deubiquitination Leukocyte Activation Involved In Immune Response B Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Stress Positive Regulation Of Viral Entry Into Host Cell Innate Immune Response Regulation Of Immune Response Immunoglobulin Secretion Regulation Of Protein Deubiquitination Phagocytosis Fc Receptor Signaling Pathway DNA Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Apoptotic Process Regulation Of Immunoglobulin Secretion Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Cytokine Production Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Lymphocyte Activation Regulation Of Viral Entry Into Host Cell Negative Regulation Of Viral Transcription Forebrain Morphogenesis Regulation Of Viral Release From Host Cell Lateral Ventricle Development Protein Destabilization Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Leukocyte Activation Regulation Of Cytokine Production Protein Trimerization
Tagcloud ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Difference) ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 cd8a ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable
Tagcloud (Intersection) ?