GRB7 and PHAX

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GRB7	PHAX
Gene Name		growth factor receptor-bound protein 7	phosphorylated adaptor for RNA export
Image
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Stress Granule Cell Projection	Nucleus Nucleoplasm Nucleolus Cytosol Cajal Body Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding SH3/SH2 Adaptor Activity Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding	RNA Binding Toxic Substance Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Blood Coagulation Positive Regulation Of Signal Transduction Negative Regulation Of Translation Positive Regulation Of Cell Migration Stress Granule Assembly Leukocyte Migration	Spliceosomal SnRNP Assembly SnRNA Export From Nucleus Gene Expression Protein Transport NcRNA Metabolic Process
Pathways		Signaling by PDGF Signaling by SCF-KIT Signaling by ERBB2 Downstream signal transduction GRB7 events in ERBB2 signaling Tie2 Signaling Cell surface interactions at the vascular wall	snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: A1BG AGAP1 ATP5B CALM1 CAV1 CPNE6 DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 FGB FLAD1 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MSH2 PDGFRB PDHB PHAX PKM PTK2 RET RND1 RPS2 SETDB1 SHC1 TEK TLE1 TMSB4X TRIM36 ZBTB16	14 interactors: ASPSCR1 GADD45G GRB7 MKNK1 NSFL1C PDPK1 RAD23A RPS6KA1 STK3 TNFSF11 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		2886	51808
HPRD ID		03311	15122
Ensembl ID		ENSG00000141738	ENSG00000164902
Uniprot IDs		Q14451	Q9H814
PDB IDs		1MW4 1WGR 2L4K 2QMS 3PQZ	2XC7
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cell Adhesion Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Intracellular Signal Transduction Immune System Process Regulation Of MAPK Cascade Regulation Of Kinase Activity Positive Regulation Of Kinase Activity Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Protein Modification Process Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Wound Healing Immune Response-regulating Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cellular Ketone Metabolic Process Regulation Of Catalytic Activity Regulation Of Immune System Process Regulation Of Signal Transduction Response To Wounding Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-amino Acid Modification Signal Transduction By Phosphorylation Positive Regulation Of Cellular Metabolic Process Response To Hormone Regulation Of Cellular Protein Metabolic Process	Regulation Of Protein Metabolic Process Response To Stress Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Apoptotic Process Programmed Cell Death Cellular Response To Growth Factor Stimulus Cell Death Death Response To Growth Factor Regulation Of Catalytic Activity Nuclear Envelope Reassembly Positive Regulation Of Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Epidermal Growth Factor Receptor Signaling Pathway Posttranscriptional Regulation Of Gene Expression Cellular Response To Stimulus Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of JNK Cascade Response To Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Cell Activation Cellular Response To Stress Positive Regulation Of Kinase Activity Regulation Of Stress-activated MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Cell Communication Positive Regulation Of Transferase Activity Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Autophagic Vacuole Assembly Positive Regulation Of Cell-cell Adhesion Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Proteasomal Protein Catabolic Process Regulation Of Signal Transduction Regulation Of Gene Expression Regulation Of Translation Activation Of Protein Kinase Activity
Tagcloud ?		adapter appears avidly bear bps conversely denote domain domains dramatically existence grb10 grb14 homology interact interaction interacts ir location loop obvious paired pleckstrin resemblance sh2 summary unidentified y1150f y1151f
Tagcloud (Difference) ?		adapter appears avidly bear bps conversely denote domain domains dramatically existence grb10 grb14 homology interact interaction interacts ir location loop obvious paired pleckstrin resemblance sh2 summary unidentified y1150f y1151f
Tagcloud (Intersection) ?