GK and AOX1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GK	AOX1
Gene Name		glycerol kinase	aldehyde oxidase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Outer Membrane Cytosol Extracellular Vesicular Exosome	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Glycerol Kinase Activity Protein Binding ATP Binding	Aldehyde Oxidase Activity Xanthine Dehydrogenase Activity Iron Ion Binding UDP-N-acetylmuramate Dehydrogenase Activity Electron Carrier Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding NAD Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glucose Homeostasis Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerol-3-phosphate Biosynthetic Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Inflammatory Response Vitamin B6 Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Reactive Oxygen Species Metabolic Process
Pathways		Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis	Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Vitamins B6 activation to pyridoxal phosphate Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS			Intelligence ( 22449649)
Protein-Protein Interactions		11 interactors: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA	5 interactors: ABCA1 CRKL GK RBL1 RCHY1
Entrez ID		2710	316
HPRD ID		08363	07537
Ensembl ID		ENSG00000198814	ENSG00000138356
Uniprot IDs		B4DH54 P32189	B4DNI5 Q06278
PDB IDs
Enriched GO Terms of Interacting Partners?		Vitamin Metabolic Process Regulation Of Translational Initiation Glycerophosphate Shuttle Cellular Response To Organic Cyclic Compound Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Positive Regulation Of Translational Initiation By Iron Negative Regulation Of Exo-alpha-sialidase Activity Steroid Hormone Mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Alkaloid Catabolic Process Hormone-mediated Signaling Pathway Xenobiotic Metabolic Process Small Molecule Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To Hormone Stimulus Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Response To Xenobiotic Stimulus Vitamin B6 Metabolic Process Glycerol-3-phosphate Catabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Monoterpenoid Metabolic Process NADH Oxidation Peroxisome Proliferator Activated Receptor Signaling Pathway Calcitriol Biosynthetic Process From Calciol Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Monocyte Differentiation Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Response To Stimulus Regulation Of Branching Involved In Prostate Gland Morphogenesis Alkaloid Metabolic Process Steroid Metabolic Process Glycerol-3-phosphate Metabolic Process Response To Organic Cyclic Compound Cellular Response To Organic Substance Positive Regulation Of Glycolytic Process Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Translation Oxidative Demethylation Chaperone-mediated Protein Complex Assembly Vitamin D Metabolic Process Muscle Organ Development Response To Hormone Regulation Of Monocyte Differentiation Positive Regulation Of Translational Initiation Endothelial Cell Chemotaxis Negative Regulation Of Acute Inflammatory Response Cellular Lipid Metabolic Process	Glycerol-3-phosphate Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Interleukin-1 Beta Secretion Glycerol Catabolic Process Apolipoprotein A-I-mediated Signaling Pathway Interleukin-1 Secretion Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Positive Regulation Of Metabolic Process Alcohol Metabolic Process Parathyroid Gland Development Platelet Dense Granule Organization Regulation Of Phosphorus Metabolic Process Phospholipid Efflux Glycerol-3-phosphate Metabolic Process Phagocytosis, Engulfment Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux Negative Regulation Of Lipid Storage Positive Regulation Of Cholesterol Transport Cellular Response To Organic Substance Regulation Of Cholesterol Efflux Response To Cholesterol Cholesterol Efflux Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cdc42 Protein Signal Transduction Cellular Carbohydrate Catabolic Process Glycerol Metabolic Process Cytokine Secretion Response To Fluid Shear Stress Regulation Of Cholesterol Transport Secretory Granule Organization Protein Autoubiquitination Triglyceride Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Anion Homeostasis
Tagcloud ?		cask channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo	autophagosomes backgroundthe compromised conclusionshigh cultivation eliminated factory g3 glycosylation heterologous immature inverted leakage mark methanol pastoris pichia popular processed prolonged quickly resultsa retention rhil rhil10 shortened unfolded varies yield
Tagcloud (Difference) ?		cask channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gkap guanylate homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo	autophagosomes backgroundthe compromised conclusionshigh cultivation eliminated factory g3 glycosylation immature inverted leakage mark methanol pastoris pichia popular processed prolonged quickly resultsa retention rhil rhil10 shortened unfolded varies yield
Tagcloud (Intersection) ?		heterologous