RNF11 and UBAC1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		RNF11	UBAC1
Gene Name		ring finger protein 11	UBA domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Ventricular conduction ( 21076409)
Protein-Protein Interactions		68 interactors: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP STAMBPL1 TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	14 interactors: AIRE APP CDKN1B CPSF6 CSNK2A1 DAZAP2 HTT LAPTM5 NEDD4L RNF11 RNF123 TRIM2 TRIM39 ZDHHC17
Entrez ID		26994	10422
HPRD ID		09955	12170
Ensembl ID		ENSG00000123091	ENSG00000130560
Uniprot IDs		Q9Y3C5	Q9BSL1
PDB IDs			2DAI
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Protein Modification Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Negative Regulation Of Signaling Toll-like Receptor 4 Signaling Pathway Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Type I Interferon Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response-regulating Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Intracellular Transport Cellular Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transforming Growth Factor Beta Receptor Signaling Pathway Protein Metabolic Process Intracellular Protein Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Cellular Response To Stimulus	Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Cellular Protein Modification Process Apoptotic Process MRNA Polyadenylation Programmed Cell Death Positive Regulation Of Cation Channel Activity Cell Death Death RNA Polyadenylation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Growth Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Proteolysis Axon Cargo Transport Mating Positive Regulation Of Transporter Activity Positive Regulation Of Cell Cycle Neuron Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Visual Learning Protein Metabolic Process Regulation Of Protein Metabolic Process Neural Plate Formation Visual Behavior Neuron Death Cellular Protein Metabolic Process Response To Metal Ion Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Ion Transmembrane Transport Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cation Channel Activity Negative Regulation Of Proteolysis Metal Ion Transport MRNA 3'-end Processing Negative Regulation Of Protein Processing Regulation Of Cell Death Associative Learning Negative Regulation Of Protein Metabolic Process Regulation Of Endopeptidase Activity Synaptic Growth At Neuromuscular Junction Serotonin Uptake Positive Regulation Of Caveolin-mediated Endocytosis Lactate Biosynthetic Process From Pyruvate Regulation Of Protein Processing Regulation Of Cell Cycle
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