UBAC1 and AIRE

Number of citations of the paper that reports this interaction (PMID 16310047)
6

Data Source:
BioGRID (two hybrid)

		UBAC1	AIRE
Gene Name		UBA domain containing 1	autoimmune regulator
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding Identical Protein Binding Transcription Regulatory Region DNA Binding Translation Regulator Activity
	Biological Process	Protein Ubiquitination	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Immune Response Humoral Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Rheumatoid arthritis ( 21505073)
Protein-Protein Interactions		14 interactors: AIRE APP CDKN1B CPSF6 CSNK2A1 DAZAP2 HTT LAPTM5 NEDD4L RNF11 RNF123 TRIM2 TRIM39 ZDHHC17	5 interactors: CREBBP DAXX HIST1H3A HIST2H2BE UBAC1
Entrez ID		10422	326
HPRD ID		12170	06301
Ensembl ID		ENSG00000130560	ENSG00000160224
Uniprot IDs		Q9BSL1	O43918
PDB IDs		2DAI	1XWH 2KE1 2KFT 2LRI
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Cellular Protein Modification Process Apoptotic Process MRNA Polyadenylation Programmed Cell Death Positive Regulation Of Cation Channel Activity Cell Death Death RNA Polyadenylation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Growth Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Proteolysis Axon Cargo Transport Mating Positive Regulation Of Transporter Activity Positive Regulation Of Cell Cycle Neuron Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Visual Learning Protein Metabolic Process Regulation Of Protein Metabolic Process Neural Plate Formation Visual Behavior Neuron Death Cellular Protein Metabolic Process Response To Metal Ion Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Ion Transmembrane Transport Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cation Channel Activity Negative Regulation Of Proteolysis Metal Ion Transport MRNA 3'-end Processing Negative Regulation Of Protein Processing Regulation Of Cell Death Associative Learning Negative Regulation Of Protein Metabolic Process Regulation Of Endopeptidase Activity Synaptic Growth At Neuromuscular Junction Serotonin Uptake Positive Regulation Of Caveolin-mediated Endocytosis Lactate Biosynthetic Process From Pyruvate Regulation Of Protein Processing Regulation Of Cell Cycle	Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Chromatin Organization DNA Packaging DNA Conformation Change Chromosome Organization Protein Complex Assembly Cellular Macromolecular Complex Assembly Cellular Component Assembly N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Germ-line Stem Cell Maintenance Organelle Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Response To Stress N-terminal Protein Amino Acid Acetylation DNA Methylation On Cytosine Chromatin Silencing At RDNA Innate Immune Response In Mucosa Regulation Of Gene Silencing Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Antibacterial Humoral Response N-terminal Protein Amino Acid Modification Antimicrobial Humoral Response Negative Regulation Of Cellular Metabolic Process Chromatin Modification Regulation Of Cellular Response To Heat Mucosal Immune Response Chromatin Silencing Activation Of JUN Kinase Activity Androgen Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Mitotic Cytokinesis Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress DNA Methylation
Tagcloud ?			adhere alive apcs behave confluency crosstalk dead differentiating fate fractionated fresh implied kill killer mdcs medullary mimic mtec mtecs named pass reproducing rescuer surprisingly tec1 tec2 thymic thymocytes tsas
Tagcloud (Difference) ?			adhere alive apcs behave confluency crosstalk dead differentiating fate fractionated fresh implied kill killer mdcs medullary mimic mtec mtecs named pass reproducing rescuer surprisingly tec1 tec2 thymic thymocytes tsas
Tagcloud (Intersection) ?