FSHB and CGA

Number of citations of the paper that reports this interaction (PMID 10563789)
1

Data Source:
HPRD (in vitro)

		FSHB	CGA
Gene Name		follicle stimulating hormone, beta polypeptide	glycoprotein hormones, alpha polypeptide
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Extracellular Vesicular Exosome	Extracellular Region
	Molecular Function	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity	Hormone Activity Protein Binding
	Biological Process	Progesterone Biosynthetic Process Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Female Pregnancy Positive Regulation Of Cell Proliferation Peptide Hormone Processing Positive Regulation Of Cell Migration Follicle-stimulating Hormone Signaling Pathway Cellular Protein Metabolic Process Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Positive Regulation Of Transcription From RNA Polymerase II Promoter Sertoli Cell Proliferation	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Peptide Hormone Processing Positive Regulation Of Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Peptide hormone metabolism GPCR downstream signaling Glycoprotein hormones Peptide hormone biosynthesis	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Amine-derived hormones Metabolism of lipids and lipoproteins Mineralocorticoid biosynthesis G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Androgen biosynthesis Metabolism of amino acids and derivatives Metabolism of steroid hormones and vitamin D Peptide hormone metabolism GPCR downstream signaling Glycoprotein hormones Thyroxine biosynthesis Peptide hormone biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CGA CGB FSHR	8 interactors: CGB CGB5 FSHB LHB LHCGR PTN PTPN12 TSHB
Entrez ID		2488	1081
HPRD ID		00644	00342
Ensembl ID		ENSG00000131808	ENSG00000135346
Uniprot IDs		P01225	P01215 Q6I9S8
PDB IDs		1FL7 1XWD 4AY9	1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Female Gamete Generation Peptide Metabolic Process Hormone Metabolic Process Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Follicle-stimulating Hormone Signaling Pathway Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cell-cell Signaling Reproduction Single Organism Reproductive Process Ovarian Follicle Development Reproductive Process	Peptide Hormone Processing Peptide Metabolic Process Hormone Metabolic Process Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Female Gamete Generation Progesterone Biosynthetic Process Male Gonad Development Single Organism Reproductive Process Progesterone Metabolic Process C21-steroid Hormone Biosynthetic Process Reproductive Process Male Sex Differentiation C21-steroid Hormone Metabolic Process Gonad Development Development Of Primary Sexual Characteristics Sex Differentiation Cell-cell Signaling Hormone Biosynthetic Process Signal Transduction Signaling Cell Communication Cellular Ketone Metabolic Process Reproductive Structure Development Reproductive System Development Steroid Biosynthetic Process Cellular Protein Metabolic Process Cellular Response To Stimulus Luteinizing Hormone Signaling Pathway Gamete Generation Developmental Process Involved In Reproduction Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Follicle-stimulating Hormone Signaling Pathway Sertoli Cell Proliferation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Protein Metabolic Process Steroid Metabolic Process Regulation Of Inositol Trisphosphate Biosynthetic Process Response To Stimulus Positive Regulation Of Inositol Phosphate Biosynthetic Process Reproduction Cognition Positive Regulation Of CAMP-mediated Signaling G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Bone Resorption Regulation Of CAMP-mediated Signaling
Tagcloud ?		11p13 11p15 aniridia band characterised closer cmgt congruent constitutional cytogenetically discrete e65 genitourinary hiking hitch hras1 hybrids locate overlap pter recombinants redefined retardation smallest subtend transformant translocations wagr wilms	aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wilms wt wt1 wts zf3 zinc
Tagcloud (Difference) ?		11p13 11p15 aniridia band characterised closer cmgt congruent constitutional cytogenetically discrete e65 genitourinary hiking hitch hras1 hybrids locate overlap pter recombinants redefined retardation smallest subtend transformant translocations wagr	aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wt wt1 wts zf3 zinc
Tagcloud (Intersection) ?		wilms