CGA and TSHB

Number of citations of the paper that reports this interaction (PMID 5002675)
23

Data Source:
HPRD (in vivo)

		CGA	TSHB
Gene Name		glycoprotein hormones, alpha polypeptide	thyroid stimulating hormone, beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Extracellular Region
	Molecular Function	Hormone Activity Protein Binding	Hormone Activity
	Biological Process	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Peptide Hormone Processing Positive Regulation Of Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Anatomical Structure Morphogenesis Peptide Hormone Processing Response To Vitamin A Response To Estrogen Cellular Protein Metabolic Process Response To Calcium Ion
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Amine-derived hormones Metabolism of lipids and lipoproteins Mineralocorticoid biosynthesis G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Androgen biosynthesis Metabolism of amino acids and derivatives Metabolism of steroid hormones and vitamin D Peptide hormone metabolism GPCR downstream signaling Glycoprotein hormones Thyroxine biosynthesis Peptide hormone biosynthesis	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Amine-derived hormones G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Metabolism of amino acids and derivatives Peptide hormone metabolism GPCR downstream signaling Glycoprotein hormones Thyroxine biosynthesis Peptide hormone biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CGB CGB5 FSHB LHB LHCGR PTN PTPN12 TSHB	2 interactors: CGA TSHR
Entrez ID		1081	7252
HPRD ID		00342	11766
Ensembl ID		ENSG00000135346	ENSG00000134200
Uniprot IDs		P01215 Q6I9S8	P01222
PDB IDs		1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Peptide Metabolic Process Hormone Metabolic Process Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Female Gamete Generation Progesterone Biosynthetic Process Male Gonad Development Single Organism Reproductive Process Progesterone Metabolic Process C21-steroid Hormone Biosynthetic Process Reproductive Process Male Sex Differentiation C21-steroid Hormone Metabolic Process Gonad Development Development Of Primary Sexual Characteristics Sex Differentiation Cell-cell Signaling Hormone Biosynthetic Process Signal Transduction Signaling Cell Communication Cellular Ketone Metabolic Process Reproductive Structure Development Reproductive System Development Steroid Biosynthetic Process Cellular Protein Metabolic Process Cellular Response To Stimulus Luteinizing Hormone Signaling Pathway Gamete Generation Developmental Process Involved In Reproduction Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Follicle-stimulating Hormone Signaling Pathway Sertoli Cell Proliferation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Protein Metabolic Process Steroid Metabolic Process Regulation Of Inositol Trisphosphate Biosynthetic Process Response To Stimulus Positive Regulation Of Inositol Phosphate Biosynthetic Process Reproduction Cognition Positive Regulation Of CAMP-mediated Signaling G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Bone Resorption Regulation Of CAMP-mediated Signaling	Thyroid-stimulating Hormone Signaling Pathway Regulation Of Locomotion Positive Regulation Of Cell Proliferation Dopaminergic Neuron Differentiation Cell-cell Signaling Inner Ear Receptor Stereocilium Organization Cochlea Morphogenesis Peptide Hormone Processing Inner Ear Receptor Cell Development Regulation Of Cell Proliferation Cochlea Development Positive Regulation Of Multicellular Organism Growth Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Inner Ear Receptor Cell Differentiation Mechanoreceptor Differentiation
Tagcloud ?		aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wilms wt wt1 wts zf3 zinc	cga deiodinase dio2 hypothalamic hypothalamus intra intraperitoneal ko littermates mct mct8 nbr neuromedin paracrine pituitary releasing slc16a2 slight t3 t4 thrb thyroid thyroidal thyrotropin thyroxine trh trhr triiodothyronine
Tagcloud (Difference) ?		aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wilms wt wt1 wts zf3 zinc	deiodinase dio2 hypothalamic hypothalamus intra intraperitoneal ko littermates mct mct8 nbr neuromedin paracrine pituitary releasing slc16a2 slight t3 t4 thrb thyroid thyroidal thyrotropin thyroxine trh trhr triiodothyronine
Tagcloud (Intersection) ?		cga