DNAJC13 and DNAJB11

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DNAJC13	DNAJB11
Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 13	DnaJ (Hsp40) homolog, subfamily B, member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Vesicular Exosome WASH Complex	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane
	Molecular Function	Protein Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Osteoblast Differentiation Endosome Organization Regulation Of Early Endosome To Recycling Endosome Transport Regulation Of Early Endosome To Late Endosome Transport	Protein Folding Activation Of Signaling Protein Activity Involved In Unfolded Protein Response MRNA Modification Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CALM1 DNAJB11 GADD45A GSK3B RPS6KA6	23 interactors: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		23317	51726
HPRD ID		10915	07485
Ensembl ID		ENSG00000138246	ENSG00000090520
Uniprot IDs		O75165	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphorylation Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Glycogen Metabolic Process Response To Stress Positive Regulation Of Protein Kinase Activity Cellular Response To Stress Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity Cellular Response To Mechanical Stimulus Polysaccharide Metabolic Process Positive Regulation Of Transferase Activity Signal Transduction In Response To DNA Damage Response To External Stimulus Regulation Of MAPK Cascade Intracellular Signal Transduction ER-nucleus Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Energy Reserve Metabolic Process Cellular Response To Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Negative Regulation Of MAPK Cascade Response To Endoplasmic Reticulum Stress Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Protein Metabolic Process Signal Transduction Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Response To Fibroblast Growth Factor Central Nervous System Development Positive Regulation Of Hydrolase Activity	Peptidyl-lysine Modification Catabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signal Transduction Response To Ionizing Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Cellular Response To Amino Acid Stimulus Cellular Heat Acclimation Regulation Of Early Endosome To Recycling Endosome Transport Cytidine To Uridine Editing Cellular Response To Leucine Formation Of Cytoplasmic Translation Initiation Complex Ossification Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Methylation-dependent Chromatin Silencing DNA Modification Positive Regulation Of Reactive Oxygen Species Metabolic Process Histone Lysine Methylation Protein Stabilization Regulation Of Protein Complex Assembly Chromatin Organization Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Regulation Of Methylation-dependent Chromatin Silencing Locomotion Regulation Of Protein Catabolic Process Axon Guidance Signal Transduction By P53 Class Mediator Response To Amino Acid
Tagcloud ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog hsp40 journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular hsp40 indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Difference) ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Intersection) ?		hsp40