DNAJC13 and GADD45A

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DNAJC13	GADD45A
Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 13	growth arrest and DNA-damage-inducible, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Vesicular Exosome WASH Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Core Promoter Binding Protein Binding
	Biological Process	Osteoblast Differentiation Endosome Organization Regulation Of Early Endosome To Recycling Endosome Transport Regulation Of Early Endosome To Late Endosome Transport	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Activation Of MAPKKK Activity DNA Repair Negative Regulation Of Protein Kinase Activity Apoptotic Process Cell Cycle Arrest Centrosome Cycle Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Cellular Response To Mechanical Stimulus Cellular Response To Ionizing Radiation Positive Regulation Of P38MAPK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CALM1 DNAJB11 GADD45A GSK3B RPS6KA6	65 interactors: ADAP1 ASCC2 AURKA BAG6 C14orf1 CCNB1 CDK1 CDK11A CDKN1A CENPB CHD3 CLEC3B DCTN2 DNAJC13 EEF1A1 EEF1G FAM83D FAS FBN3 FTL GADD45GIP1 GAPDH GBP2 GNB2 HIST1H1A HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 IGHM IGSF21 JMJD1C KHSRP LMO4 MAP3K4 MAPK14 MASP1 MDM2 MICAL1 MIDN MPP1 NPM1 NRBP1 NUCB2 PCNA PFKFB4 PPARA PSMC3 PTN PTPRK QARS RAI1 RBPJ RPS2 RXRA SH3GLB1 SPTBN4 SYNE4 TLE1 TP53 UBE2D1 UBR1 VIM ZHX1 ZNF135
Entrez ID		23317	1647
HPRD ID		10915	00528
Ensembl ID		ENSG00000138246	ENSG00000116717
Uniprot IDs		O75165	A5JUZ3 P24522
PDB IDs			2KG4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphorylation Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Glycogen Metabolic Process Response To Stress Positive Regulation Of Protein Kinase Activity Cellular Response To Stress Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity Cellular Response To Mechanical Stimulus Polysaccharide Metabolic Process Positive Regulation Of Transferase Activity Signal Transduction In Response To DNA Damage Response To External Stimulus Regulation Of MAPK Cascade Intracellular Signal Transduction ER-nucleus Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Energy Reserve Metabolic Process Cellular Response To Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Negative Regulation Of MAPK Cascade Response To Endoplasmic Reticulum Stress Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Protein Metabolic Process Signal Transduction Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Response To Fibroblast Growth Factor Central Nervous System Development Positive Regulation Of Hydrolase Activity	Regulation Of Metabolic Process Cell Cycle Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Mitotic Cell Cycle Process Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Organelle Organization DNA Packaging DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Organization Cell Aging Protein Complex Assembly Chromatin Organization Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Death Death Positive Regulation Of Protein Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance DNA Damage Checkpoint Chromatin Assembly Or Disassembly Stress-induced Premature Senescence Immune Response Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Mitotic DNA Damage Checkpoint Immune System Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cell Death Positive Regulation Of Metabolic Process Innate Immune Response Mitotic DNA Integrity Checkpoint Response To Toxic Substance Positive Regulation Of Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Cellular Response To Oxygen Levels
Tagcloud ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog hsp40 journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog hsp40 journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?