FANCD2 and FANCI

Number of citations of the paper that reports this interaction (PMID 17460694)
70

Data Source:
HPRD (in vitro)

		FANCD2	FANCI
Gene Name		Fanconi anemia, complementation group D2	Fanconi anemia, complementation group I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding DNA Polymerase Binding	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	DNA Repair Synapsis Gamete Generation Response To Gamma Radiation	DNA Repair Cell Cycle Positive Regulation Of Protein Ubiquitination
Pathways		Fanconi Anemia pathway Regulation of the Fanconi anemia pathway	Fanconi Anemia pathway Regulation of the Fanconi anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ATM ATR BLM BRCA1 BRCA2 FANCC FANCE FANCI FANCL MEN1 MRE11A NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB USP1	4 interactors: APP FANCD2 FANCL WDR48
Entrez ID		2177	55215
HPRD ID		01968	13339
Ensembl ID		ENSG00000144554	ENSG00000140525
Uniprot IDs		Q9BXW9	B3KNW8 Q9NVI1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Regulation Of DNA Replication Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Cycle DNA Recombination Cell Cycle Process Response To Stress Double-strand Break Repair Negative Regulation Of DNA Replication Cell Cycle Checkpoint Response To Ionizing Radiation DNA Damage Checkpoint Telomere Maintenance DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process G2 DNA Damage Checkpoint Negative Regulation Of DNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Stimulus Nitrogen Compound Metabolic Process Response To Stimulus Mitotic G2 DNA Damage Checkpoint Regulation Of Protein Metabolic Process Response To Radiation Negative Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Checkpoint Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Cellular Metabolic Process Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Signal Transduction By P53 Class Mediator Mitotic Cell Cycle Process Chromosome Organization Regulation Of Response To DNA Damage Stimulus Mitotic Cell Cycle	Sexual Reproduction Reproduction Reproductive Process DNA Repair Gamete Generation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cellular Response To DNA Damage Stimulus Regulation Of Protein Monoubiquitination Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Response To Stress Collateral Sprouting In Absence Of Injury Single Organism Reproductive Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stress Axon Choice Point Recognition Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Growth Seminiferous Tubule Development Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Monoubiquitination Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Response To Gamma Radiation Cellular Protein Modification Process
Tagcloud ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Difference) ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Intersection) ?