ETS2 and SRA1

Number of citations of the paper that reports this interaction (PMID 20398657)
4

Data Source:
BioGRID (far western blotting)

		ETS2	SRA1
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog 2	steroid receptor RNA activator 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Microtubule Cytoskeleton Ribonucleoprotein Complex Intercellular Bridge
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Glucocorticoid Receptor Binding	Transcription Coactivator Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Cell Proliferation Cell Differentiation Regulation Of Apoptotic Process Positive Regulation Of Receptor Activity
Pathways		Cellular Senescence Oncogene Induced Senescence
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 21079520)
Protein-Protein Interactions		20 interactors: CDK10 CREBBP EP300 ERG ETS1 FOS GATA3 JUN NCOR1 NR3C1 POU5F1 RFWD2 SMARCA4 SPI1 SRA1 SRC STAT5B TDP2 ZFYVE9 ZMYND11	33 interactors: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DDX17 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NCOA2 NR3C1 RXRB TFAP2A UBE2Z
Entrez ID		2114	10011
HPRD ID		01263	18716
Ensembl ID		ENSG00000157557	ENSG00000213523
Uniprot IDs		P15036	Q9HD15
PDB IDs		4BQA 4MHV
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Cell Cycle Regulation Of Signal Transduction Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Myeloid Cell Differentiation Positive Regulation By Host Of Viral Transcription Response To Steroid Hormone Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of Signaling Gland Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Nitrogen Compound Metabolic Process Response To Lipid Biosynthetic Process Leukocyte Differentiation Immune System Process Cellular Response To Growth Factor Stimulus Regulation Of Myeloid Cell Differentiation Response To Organic Cyclic Compound Tissue Development	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Response To Hormone Regulation Of Metabolic Process Response To Organic Cyclic Compound Negative Regulation Of Gene Expression Cellular Response To Organic Substance Response To Organic Substance Cellular Response To Hormone Stimulus Response To Steroid Hormone Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Skeletal Muscle Cell Differentiation System Development DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Tissue Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Striated Muscle Tissue Development Response To Lipid Organ Development
Tagcloud ?		3t3 activates ap blocked colony confirming constitutive cotransfected cotransfection dominant downstream erbb families focus mutants neu neut nih oncogenic parallel points raf ras reporter residue threonine transforming transmembrane	activator adipocyte adipose biology coactivator coding diet droplets evidenced fasting fat feeding fewer glucoses homeostasis ip knock lean lipogenesis livers obesity organs ppargamma promotes regulator steroid subset tnfalpha
Tagcloud (Difference) ?		3t3 activates ap blocked colony confirming constitutive cotransfected cotransfection dominant downstream erbb families focus mutants neu neut nih oncogenic parallel points raf ras reporter residue threonine transforming transmembrane	activator adipocyte adipose biology coactivator coding diet droplets evidenced fasting fat feeding fewer glucoses homeostasis ip knock lean lipogenesis livers obesity organs ppargamma promotes regulator steroid subset tnfalpha
Tagcloud (Intersection) ?