EFNB2 and RGS3

Number of citations of the paper that reports this interaction (PMID 15458844)
39

Data Source:
HPRD (two hybrid)

		EFNB2	RGS3
Gene Name		ephrin-B2	regulator of G-protein signaling 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Ephrin Receptor Binding	GTPase Activator Activity
	Biological Process	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Anatomical Structure Morphogenesis Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Viral Process Ephrin Receptor Signaling Pathway Regulation Of Chemotaxis Positive Regulation Of Cardiac Muscle Cell Differentiation	Inactivation Of MAPK Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC	22 interactors: ACD APP CNKSR2 EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PARK2 PAX6 PLSCR1 SCN5A YWHAB YWHAE YWHAQ YWHAZ
Entrez ID		1948	5998
HPRD ID		02754	03720
Ensembl ID		ENSG00000125266	ENSG00000138835
Uniprot IDs		P52799	B3KUB2 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3 Q8NFN6
PDB IDs		2HLE 2I85 2VSK 2VSM 2WO2 3GXU	2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Neuron Development Axon Guidance Neuron Differentiation Generation Of Neurons Neurogenesis Axonogenesis Cell Development Axon Development Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Projection Organization Neuron Projection Morphogenesis Regulation Of Signaling Locomotion Cell Morphogenesis Involved In Differentiation Nervous System Development Movement Of Cell Or Subcellular Component Cell Projection Morphogenesis Cell Part Morphogenesis Dendritic Spine Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Cell Differentiation Response To External Stimulus Cell Morphogenesis System Development Cell Migration Signal Transduction Synaptic Transmission Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Dendritic Spine Morphogenesis Cell Motility Regulation Of MAPK Cascade Multicellular Organismal Development Regulation Of Phosphorylation Signaling Cell Communication Anatomical Structure Development Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Component Organization Regulation Of Synaptic Transmission Dendritic Spine Development Regulation Of Synaptic Plasticity Developmental Process Behavior	Positive Regulation Of Mitochondrion Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway System Development Platelet Activation Cell-cell Signaling Positive Regulation Of Apoptotic Signaling Pathway Axon Guidance Multicellular Organismal Development Signaling Nervous System Development Anatomical Structure Development Cell Communication Response To Wounding Regulation Of Apoptotic Process Regulation Of Signaling Regulation Of Cell Death Regulation Of Cellular Process Axonogenesis Developmental Process Locomotion Axon Development Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Dephosphorylation Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Response To Stress Positive Regulation Of Programmed Cell Death Chemotaxis Cellular Response To Stimulus Positive Regulation Of Cell Death Response To External Stimulus Apoptotic Process Neuron Projection Morphogenesis Regulation Of Catalytic Activity Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Cell Death Death Cell Surface Receptor Signaling Pathway Blood Coagulation Cell Morphogenesis Involved In Differentiation Hemostasis Positive Regulation Of Transport Response To Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport
Tagcloud ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Difference) ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Intersection) ?