RGS3 and HES4

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		RGS3	HES4
Gene Name		regulator of G-protein signaling 3	hes family bHLH transcription factor 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Nucleus
	Molecular Function	GTPase Activator Activity	DNA Binding Transcription Factor Binding Protein Dimerization Activity
	Biological Process	Inactivation Of MAPK Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACD APP CNKSR2 EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PARK2 PAX6 PLSCR1 SCN5A YWHAB YWHAE YWHAQ YWHAZ	5 interactors: COPG2 LTN1 PCBD1 PCBD2 RGS3
Entrez ID		5998	57801
HPRD ID		03720	16273
Ensembl ID		ENSG00000138835	ENSG00000188290
Uniprot IDs		B3KUB2 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3 Q8NFN6	D6REB3 E9PB28 Q9HCC6
PDB IDs		2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrion Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway System Development Platelet Activation Cell-cell Signaling Positive Regulation Of Apoptotic Signaling Pathway Axon Guidance Multicellular Organismal Development Signaling Nervous System Development Anatomical Structure Development Cell Communication Response To Wounding Regulation Of Apoptotic Process Regulation Of Signaling Regulation Of Cell Death Regulation Of Cellular Process Axonogenesis Developmental Process Locomotion Axon Development Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Dephosphorylation Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Response To Stress Positive Regulation Of Programmed Cell Death Chemotaxis Cellular Response To Stimulus Positive Regulation Of Cell Death Response To External Stimulus Apoptotic Process Neuron Projection Morphogenesis Regulation Of Catalytic Activity Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Cell Death Death Cell Surface Receptor Signaling Pathway Blood Coagulation Cell Morphogenesis Involved In Differentiation Hemostasis Positive Regulation Of Transport Response To Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport	Tetrahydrobiopterin Biosynthetic Process Pteridine-containing Compound Biosynthetic Process Pteridine-containing Compound Metabolic Process Protein Homotetramerization Protein Tetramerization Protein Heterooligomerization Coenzyme Biosynthetic Process Protein Homooligomerization Cofactor Metabolic Process L-phenylalanine Catabolic Process L-phenylalanine Metabolic Process Protein Oligomerization Regulation Of Protein Homodimerization Activity
Tagcloud ?			brains contributions cpg dysregulation epigenome excessive gpr3 h3k4me3 hairy hd htt huntington hypermethylation jagged2 lastly mapping mark mash1 methylated modifying neurodegeneration pdia6 prefrontal shrna split striatal strikingly tmem106b trimethyl
Tagcloud (Difference) ?			brains contributions cpg dysregulation epigenome excessive gpr3 h3k4me3 hairy hd htt huntington hypermethylation jagged2 lastly mapping mark mash1 methylated modifying neurodegeneration pdia6 prefrontal shrna split striatal strikingly tmem106b trimethyl
Tagcloud (Intersection) ?