EDA and GIMAP5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EDA	GIMAP5
Gene Name		ectodysplasin A	GTPase, IMAP family member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell	Mitochondrial Outer Membrane Lysosome Integral Component Of Membrane
	Molecular Function	Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding	GTP Binding
	Biological Process	Immune Response Cell-matrix Adhesion Signal Transduction Ectoderm Development Gene Expression Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Pigmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
Protein-Protein Interactions		15 interactors: ATP6V0C CYB561 DOLK EDA2R EDAR EMP3 FURIN GIMAP5 LEPROTL1 MAL NIPAL3 OSTC OSTCP1 PLN SEC22A	6 interactors: APP EDA GRAMD3 LDLRAD1 LSMEM2 STX4
Entrez ID		1896	55340
HPRD ID		02347	16280
Ensembl ID		ENSG00000158813	ENSG00000196329
Uniprot IDs		Q92838	Q96F15
PDB IDs		1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-15 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Dolichyl Monophosphate Biosynthetic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein N-linked Glycosylation Via Asparagine Cell Death Death Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Receptor Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein N-linked Glycosylation Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Nerve Growth Factor Processing G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Membrane Raft Localization Dolichyl Diphosphate Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Transforming Growth Factor Beta Production Ectodermal Cell Differentiation Regulation Of JNK Cascade Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Salivary Gland Cavitation Regulation Of Stress-activated MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Post-translational Protein Modification Transport	Platelet Activation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Collateral Sprouting In Absence Of Injury Trachea Gland Development Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Protein Transport Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Salivary Gland Cavitation Positive Regulation Of Protein Localization To Cell Surface Blood Coagulation Response To Oxidative Stress Hemostasis Positive Regulation Of Immunoglobulin Secretion Neuron Remodeling SNARE Complex Assembly Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Regulation Of Signal Transduction Regulation Of Body Fluid Levels Regulation Of Immunoglobulin Secretion Wound Healing Regulation Of Protein Transport Secretion Hair Follicle Placode Formation Cellular Copper Ion Homeostasis Regulation Of Signaling Regulation Of Establishment Of Protein Localization Cell Activation Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Response To Wounding Positive Regulation Of NF-kappaB Import Into Nucleus Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Transport Response To Hydroperoxide Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ectoderm Development Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Trachea Development
Tagcloud ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness	adipocyte adipocytes adipogenesis adiponectin adipose autonomous biogenesis ca calcineurin causative cisd2 cytosolic defects epididymal ewat functioning homeostasis knockout ko maintenance mitochondria modulate mystery played resolve seem wat wfs wolfram
Tagcloud (Difference) ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls showing sweating tonic unrelated weakness	adipocyte adipocytes adipogenesis adiponectin adipose autonomous biogenesis ca calcineurin causative cisd2 cytosolic defects epididymal ewat functioning homeostasis knockout ko maintenance mitochondria modulate mystery played resolve wat wfs wolfram
Tagcloud (Intersection) ?		seem