EDA and SEC22A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EDA	SEC22A
Gene Name		ectodysplasin A	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell	Endoplasmic Reticulum Membrane Integral Component Of Membrane SNARE Complex
	Molecular Function	Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding	SNARE Binding Transporter Activity SNAP Receptor Activity
	Biological Process	Immune Response Cell-matrix Adhesion Signal Transduction Ectoderm Development Gene Expression Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Pigmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway	Exocytosis ER To Golgi Vesicle-mediated Transport Protein Transport Vesicle Fusion With Golgi Apparatus
Pathways
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
Protein-Protein Interactions		15 interactors: ATP6V0C CYB561 DOLK EDA2R EDAR EMP3 FURIN GIMAP5 LEPROTL1 MAL NIPAL3 OSTC OSTCP1 PLN SEC22A	10 interactors: DTX2 EDA ERLIN1 FATE1 MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79
Entrez ID		1896	26984
HPRD ID		02347	15313
Ensembl ID		ENSG00000158813
Uniprot IDs		Q92838	Q96IW7
PDB IDs		1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-15 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Dolichyl Monophosphate Biosynthetic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein N-linked Glycosylation Via Asparagine Cell Death Death Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Receptor Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein N-linked Glycosylation Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Nerve Growth Factor Processing G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Membrane Raft Localization Dolichyl Diphosphate Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Transforming Growth Factor Beta Production Ectodermal Cell Differentiation Regulation Of JNK Cascade Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Salivary Gland Cavitation Regulation Of Stress-activated MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Post-translational Protein Modification Transport	ER-associated Ubiquitin-dependent Protein Catabolic Process Hair Follicle Development Hair Cycle Process Hair Cycle Positive Regulation Of Eosinophil Degranulation Cuticle Development ER-associated Misfolded Protein Catabolic Process Cornification Trachea Gland Development Establishment Of Epithelial Cell Apical/basal Polarity Salivary Gland Cavitation Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Skin Development Positive Regulation Of Immunoglobulin Secretion Establishment Of Monopolar Cell Polarity SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Synaptic Vesicle Fusion To Presynaptic Membrane Epidermis Development Cellular Response To Nitric Oxide Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Immunoglobulin Secretion Regulation Of Autophagic Vacuole Assembly Response To Misfolded Protein Response To Nitric Oxide Epithelium Development Positive Regulation Of Protein Transport Positive Regulation Of Cholesterol Storage Establishment Of Skin Barrier Establishment Of Epithelial Cell Polarity Exocytosis Hair Follicle Placode Formation Regulation Of Vacuole Organization Lipoprotein Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Epithelial Cell Maturation Positive Regulation Of NF-kappaB Import Into Nucleus
Tagcloud ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Difference) ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Intersection) ?