DLX5 and MAGED1

Number of citations of the paper that reports this interaction (PMID 11084035)
17

Data Source:
HPRD (in vivo, two hybrid)

		DLX5	MAGED1
Gene Name		distal-less homeobox 5	melanoma antigen family D, 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Cytoplasm	Chromatin Nucleus Cytoplasm Plasma Membrane Protein Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Regulatory Region DNA Binding HMG Box Domain Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Skeletal System Development Osteoblast Differentiation Endochondral Ossification Transcription, DNA-templated Nervous System Development Axon Guidance Cell Proliferation Embryonic Limb Morphogenesis BMP Signaling Pathway Epithelial Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription, DNA-templated Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Palate Development Olfactory Pit Development Face Morphogenesis Cellular Response To BMP Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK Programmed Cell Death p75 NTR receptor-mediated signalling Role of DCC in regulating apoptosis Extrinsic Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: DLX2 HOXC8 MAGED1 MSX1 MSX2 NCOA2 SOX10 SOX8 SPEN	49 interactors: AKAP9 BAG3 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 HIVEP1 KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 ROR2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488
Entrez ID		1749	9500
HPRD ID		02492	02202
Ensembl ID		ENSG00000105880	ENSG00000179222
Uniprot IDs		P56178 Q53Y73	Q9Y5V3
PDB IDs		2DJN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Mesenchymal Cell Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Mesenchymal Cell Apoptotic Process Embryonic Nail Plate Morphogenesis Mesenchyme Development Activation Of Meiosis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process BMP Signaling Pathway Involved In Heart Development Connective Tissue Development Stem Cell Development Skeletal System Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Differentiation Nail Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Regulation Of Gliogenesis Transcription From RNA Polymerase II Promoter Odontogenesis Of Dentin-containing Tooth Enteric Nervous System Development Odontogenesis Organ Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Pattern Specification Process Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Meiotic Nuclear Division Endocardial Cushion Formation RNA Metabolic Process Embryo Development Regulation Of Branching Involved In Ureteric Bud Morphogenesis	Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Binding Transcription, DNA-templated Metabolic Process Signal Transduction Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Cellular Response To Stimulus Positive Regulation Of Signal Transduction RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Signaling Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Embryo Development Radial Glia Guided Migration Of Purkinje Cell Cellular Process Macromolecule Biosynthetic Process Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Communication Positive Regulation Of Metabolic Process System Development Apoptotic Process Response To Stimulus
Tagcloud ?		acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx2 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Difference) ?		acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx2 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Intersection) ?