SGOL1 and RPL28

Number of citations of the paper that reports this interaction (PMID 16541025)
118

Data Source:
HPRD (in vivo)

		SGOL1	RPL28
Gene Name		shugoshin-like 1 (S. pombe)	ribosomal protein L28
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Chromosome, Centromeric Region Condensed Nuclear Chromosome, Centromeric Region Spindle Pole Nucleoplasm Cytoplasm Centrosome Cytosol Mitotic Cohesin Complex	Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Dendrite Cytoplasmic Ribonucleoprotein Granule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Centriole-centriole Cohesion Meiotic Chromosome Segregation Cell Division	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Temperament (bipolar disorder) ( 22365631)
Protein-Protein Interactions		21 interactors: CDCA8 LRRC59 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET UBC XRCC5 XRCC6	6 interactors: CCNDBP1 MAP2K5 SGOL1 SMAD4 STAU1 TMEM230
Entrez ID		151648	6158
HPRD ID		12377	04702
Ensembl ID		ENSG00000129810	ENSG00000108107
Uniprot IDs		B5BUA4 Q5FBB7	H0YKD8 P46779
PDB IDs		3FGA 3Q6S 4A0I	3J3B
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process Viral Process Viral Life Cycle Viral Transcription Protein Complex Disassembly SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Catabolic Process Aromatic Compound Catabolic Process Protein Localization To Endoplasmic Reticulum Translational Termination MRNA Metabolic Process Protein Targeting To Membrane Membrane Organization Translational Elongation Cellular Protein Complex Disassembly Positive Regulation Of Type I Interferon Production Double-strand Break Repair Via Nonhomologous End Joining Cellular Hyperosmotic Salinity Response Establishment Of Protein Localization To Membrane Translational Initiation Mitotic Cell Cycle Regulation Of Type I Interferon Production Cellular Response To X-ray Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Establishment Of Protein Localization To Organelle Apoptotic Process Fibroblast Growth Factor Receptor Signaling Pathway Protein Localization To Membrane Programmed Cell Death Mitotic Cell Cycle Process Cell Death Death Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cytoplasmic Transport Cellular Response To Stress Establishment Of Integrated Proviral Latency Cellular Response To Fibroblast Growth Factor Stimulus Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Fibroblast Growth Factor Cellular Hyperosmotic Response Hyperosmotic Salinity Response Protein Targeting	Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production ERK5 Cascade Nephrogenic Mesenchyme Morphogenesis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Negative Regulation Of Interleukin-8 Biosynthetic Process Endocardial Cell Differentiation Centriole-centriole Cohesion Negative Regulation Of Heterotypic Cell-cell Adhesion Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Formation Of Anatomical Boundary Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Endothelial Cell Activation Regulation Of Transforming Growth Factor Beta2 Production Regulation Of Cell Growth Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Intracellular MRNA Localization Regulation Of Interleukin-8 Biosynthetic Process Attachment Of Spindle Microtubules To Kinetochore Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Brainstem Development SMAD Protein Complex Assembly Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Canal Development Negative Regulation Of Interleukin-8 Production Regulation Of Hair Follicle Development Heart Valve Formation Metanephric Mesenchyme Development Endocardial Cushion Formation Endocardium Development Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Fluid Shear Stress Atrioventricular Valve Morphogenesis Response To Laminar Fluid Shear Stress Regulation Of Sprouting Angiogenesis Regulation Of Hair Cycle Negative Regulation Of Blood Vessel Endothelial Cell Migration Endocardial Cushion Morphogenesis Atrioventricular Valve Development Heart Development Positive Regulation Of Viral Genome Replication Cardiac Epithelial To Mesenchymal Transition Regulation Of Cytokine Production Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 subtype ttk tumorigenic upregulated
Tagcloud (Difference) ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 subtype ttk tumorigenic upregulated
Tagcloud (Intersection) ?