SGOL1 and RPL7A

Number of citations of the paper that reports this interaction (PMID 16541025)
118

Data Source:
HPRD (in vivo)

		SGOL1	RPL7A
Gene Name		shugoshin-like 1 (S. pombe)	ribosomal protein L7a
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Chromosome, Centromeric Region Condensed Nuclear Chromosome, Centromeric Region Spindle Pole Nucleoplasm Cytoplasm Centrosome Cytosol Mitotic Cohesin Complex	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Centriole-centriole Cohesion Meiotic Chromosome Segregation Cell Division	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosome Biogenesis Cellular Protein Metabolic Process
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Temperament (bipolar disorder) ( 22365631)
Protein-Protein Interactions		21 interactors: CDCA8 LRRC59 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET UBC XRCC5 XRCC6	7 interactors: CCDC47 CTBP2 MKNK2 POLR2M SGOL1 SOCS3 STAU1
Entrez ID		151648	6130
HPRD ID		12377	01712
Ensembl ID		ENSG00000129810	ENSG00000148303
Uniprot IDs		B5BUA4 Q5FBB7	P62424
PDB IDs		3FGA 3Q6S 4A0I	3J3B
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process Viral Process Viral Life Cycle Viral Transcription Protein Complex Disassembly SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Catabolic Process Aromatic Compound Catabolic Process Protein Localization To Endoplasmic Reticulum Translational Termination MRNA Metabolic Process Protein Targeting To Membrane Membrane Organization Translational Elongation Cellular Protein Complex Disassembly Positive Regulation Of Type I Interferon Production Double-strand Break Repair Via Nonhomologous End Joining Cellular Hyperosmotic Salinity Response Establishment Of Protein Localization To Membrane Translational Initiation Mitotic Cell Cycle Regulation Of Type I Interferon Production Cellular Response To X-ray Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Establishment Of Protein Localization To Organelle Apoptotic Process Fibroblast Growth Factor Receptor Signaling Pathway Protein Localization To Membrane Programmed Cell Death Mitotic Cell Cycle Process Cell Death Death Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cytoplasmic Transport Cellular Response To Stress Establishment Of Integrated Proviral Latency Cellular Response To Fibroblast Growth Factor Stimulus Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Fibroblast Growth Factor Cellular Hyperosmotic Response Hyperosmotic Salinity Response Protein Targeting	Maintenance Of ER Location Maintenance Of Location In Cell Positive Regulation By Virus Of Viral Protein Levels In Host Cell Endoplasmic Reticulum Localization Spongiotrophoblast Differentiation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Centriole-centriole Cohesion Positive Regulation Of Chromatin Binding
Tagcloud ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 subtype ttk tumorigenic upregulated	arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Difference) ?		amongst brdu ca centrosome conversely discerning downregulated duplication explored hcc1954 incorporation instability kaplan knockdown manipulation mcf10a mdm2 meier microarray modulators novelty plot pursued resource sfrp1 subtype ttk tumorigenic upregulated	arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Intersection) ?