PTPRT and PTPRN

Number of citations of the paper that reports this interaction (PMID 16273344)
7

Data Source:
HPRD (two hybrid, in vitro)

		PTPRT	PTPRN
Gene Name		protein tyrosine phosphatase, receptor type, T	protein tyrosine phosphatase, receptor type, N
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Beta-catenin Binding Alpha-catenin Binding Gamma-catenin Binding Cadherin Binding Delta-catenin Binding	Protein Tyrosine Phosphatase Activity Protein Binding Spectrin Binding GTPase Binding
	Biological Process	Protein Dephosphorylation Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Dephosphorylation	Response To Reactive Oxygen Species Protein Dephosphorylation Response To Glucose Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Response To Estrogen Response To CAMP Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: PTPRN	13 interactors: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4
Entrez ID		11122	5798
HPRD ID		06690	03466
Ensembl ID		ENSG00000196090	ENSG00000054356
Uniprot IDs		O14522	Q16849 Q96IA0
PDB IDs		2OOQ	2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?		Dense Core Granule Maturation Insulin Secretion Peptide Hormone Secretion Peptide Secretion Hormone Secretion Hormone Transport Peptide Transport Response To CAMP Protein Secretion Response To Glucose Amide Transport Response To Organophosphorus Response To Purine-containing Compound Peptidyl-tyrosine Dephosphorylation Response To Carbohydrate Response To Reactive Oxygen Species Response To Estrogen Vesicle Organization Protein Dephosphorylation Regulation Of Hormone Levels Response To Insulin	Myoblast Fusion Central Nervous System Development Syncytium Formation Regulation Of Cellular Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Adult Walking Behavior Regulation Of Protein Metabolic Process Myotube Differentiation Cell Differentiation Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Uncoating Of Virus Anatomical Structure Development Response To Stimulus Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Interaction With Host Spinal Cord Development Adult Locomotory Behavior Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Serotonin Uptake Membrane Raft Polarization Viral Release From Host Cell Developmental Process Muscle Structure Development Signaling Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of The Force Of Heart Contraction Regulation Of Generation Of L-type Calcium Current Cell Communication Regulation Of Neurotransmitter Levels Cell Maturation Myelination Peptidyl-cysteine S-nitrosylation Membrane Raft Localization Axon Ensheathment Regulation Of Adrenergic Receptor Signaling Pathway Age-dependent Response To Oxidative Stress Regulation Of Heart Contraction Adult Behavior Peptidyl-tyrosine Dephosphorylation
Tagcloud ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver epha3 extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Difference) ?		arid2 asxl3 cdkn2a clonal clone dipyrimidine driver epha3 extension founding geographic hypermutator lacked mel9 melanoma mll2 nras phosphatases ptprb ptprd rb1 signature strikingly subclonal subclones suppressors transitions truncation wgs	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Intersection) ?