TPPP and GAPDH

Number of citations of the paper that reports this interaction (PMID 17027006)
6

Data Source:
HPRD (in vitro, in vivo)

		TPPP	GAPDH
Gene Name		tubulin polymerization promoting protein	glyceraldehyde-3-phosphate dehydrogenase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex
	Molecular Function	Protein Binding Microtubule Binding Tubulin Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding
	Biological Process	Microtubule Bundle Formation Positive Regulation Of Protein Complex Assembly Positive Regulation Of Protein Polymerization Microtubule Polymerization	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma
Pathways			Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs			NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS		Ulcerative colitis ( 20228799)
Protein-Protein Interactions		5 interactors: APP CDK11B GAPDH GSK3B HDAC6	75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ
Entrez ID		11076	2597
HPRD ID		18522	00713
Ensembl ID		ENSG00000171368	ENSG00000111640
Uniprot IDs		O94811 Q4L233	P04406
PDB IDs			1U8F 1ZNQ 2FEH 3GPD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Apoptotic Process Programmed Cell Death Cell Death Death Cellular Protein Modification Process Neuron Apoptotic Process Cellular Response To Heat Neuron Death Regulation Of Growth Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Peptidyl-cysteine S-trans-nitrosylation Hsp90 Deacetylation Regulation Of Proteolysis Cellular Protein Metabolic Process Response To Heat Regulation Of Cellular Protein Metabolic Process Regulation Of Receptor Activity Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Innate Immune Response Regulation Of Protein Binding Regulation Of Gene Expression Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Chaperone-mediated Protein Complex Assembly Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Polyubiquitinated Misfolded Protein Transport Regulation Of Microtubule-based Process Positive Regulation Of Protein Complex Assembly Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Peptidyl-amino Acid Modification Response To Temperature Stimulus Negative Regulation Of Neuron Differentiation Protein Metabolic Process Regulation Of Gene Expression, Epigenetic Hypermethylation Of CpG Island Negative Regulation Of Hydrogen Peroxide Metabolic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Response To Abiotic Stimulus Peptidyl-cysteine S-nitrosylation Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Interleukin-3 Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition
Tagcloud ?		anterior compensatory corticospinal counted densitometry diseased emphasized emphasizes harbor horn horns immunolabeling inclusions lcs lcss mbp myelin oligodendrocyte oligodendrocytes oligodendroglia oligodendroglial p25 p62 perineuronal pnogs presentations proteinopathies suggestive tracts	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Difference) ?		anterior compensatory corticospinal counted densitometry diseased emphasized emphasizes harbor horn horns immunolabeling inclusions lcs lcss mbp myelin oligodendrocyte oligodendrocytes oligodendroglia oligodendroglial p25 p62 perineuronal pnogs presentations proteinopathies suggestive tracts	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Intersection) ?