GAPDH and OSTF1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GAPDH	OSTF1
Gene Name		glyceraldehyde-3-phosphate dehydrogenase	osteoclast stimulating factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex	Intracellular Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding	Protein Binding SH3 Domain Binding
	Biological Process	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma	Ossification Signal Transduction
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	12 interactors: APP CBL EFS FASLG GAPDH HTT KHDRBS1 MAPK6 REL SDCBP SMN1 TRIM54
Entrez ID		2597	26578
HPRD ID		00713	17808
Ensembl ID		ENSG00000111640	ENSG00000134996
Uniprot IDs		P04406	Q92882
PDB IDs		1U8F 1ZNQ 2FEH 3GPD	1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?		Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition	Neuron Apoptotic Process Neuron Death Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of ERBB Signaling Pathway Signal Transduction Positive Regulation Of Signal Transduction Signaling Cell Communication Positive Regulation Of Intracellular Signal Transduction Response To Stimulus Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Translation Axon Cargo Transport Mating Positive Regulation Of Transport Regulation Of Neuron Death Microtubule-based Process Visual Learning Visual Behavior Neural Plate Formation Peptidyl-cysteine S-trans-nitrosylation Associative Learning Synaptic Growth At Neuromuscular Junction Serotonin Uptake Positive Regulation Of RNA Export From Nucleus Lactate Biosynthetic Process From Pyruvate Apoptotic Process MRNA Processing Regulation Of Intracellular Signal Transduction Programmed Cell Death Posttranscriptional Regulation Of Gene Expression Cell Death Death Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Collateral Sprouting In Absence Of Injury Regulation Of Protein Phosphatase Type 2A Activity Endosomal Lumen Acidification Regulation Of Receptor Activity Pyruvate Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Retinal Cell Programmed Cell Death Microtubule-based Transport MRNA Metabolic Process Learning Cytoskeleton-dependent Intracellular Transport
Tagcloud ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	acad euryhaline fiol gills gilz hyperosmolality hyperosmotic hypertonicity kultz mimcd3 mosmol mossambicus natl oreochromis orthologs osmolytes osmosensory osmotic papilla proc tilapia tsc22d tsc22d1 tsc22d2 tsc22d3 tsc22d4 unresponsive usa102 zipper
Tagcloud (Difference) ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	acad euryhaline fiol gills gilz hyperosmolality hyperosmotic hypertonicity kultz mimcd3 mosmol mossambicus natl oreochromis orthologs osmolytes osmosensory osmotic papilla proc tilapia tsc22d tsc22d1 tsc22d2 tsc22d3 tsc22d4 unresponsive usa102 zipper
Tagcloud (Intersection) ?