SLC27A2 and PEX5

Number of citations of the paper that reports this interaction (PMID 20178365)
7

Data Source:
BioGRID (unspecified method)

		SLC27A2	PEX5
Gene Name		solute carrier family 27 (fatty acid transporter), member 2	peroxisomal biogenesis factor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity Receptor Binding ATP Binding Fatty Acid Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Bile Acid Metabolic Process Very Long-chain Fatty Acid Catabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Long-chain Fatty Acid Import Methyl-branched Fatty Acid Metabolic Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways		Alpha-oxidation of phytanate Bile acid and bile salt metabolism Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts Peroxisomal lipid metabolism
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		3 interactors: ABCD1 PEX5 YWHAQ	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		11001	5830
HPRD ID		11935	02684
Ensembl ID		ENSG00000140284	ENSG00000139197
Uniprot IDs		O14975	B4DR50 B4E0T2 P50542
PDB IDs			1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Peroxisomal Membrane Transport Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Peroxisomal Long-chain Fatty Acid Import Lipid Modification Carboxylic Acid Catabolic Process Negative Regulation Of Protein Homotetramerization Intracellular Transport Lipid Catabolic Process Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Fatty Acid Metabolic Process Establishment Of Localization In Cell Very Long-chain Fatty Acid Catabolic Process Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Protein Targeting Long-chain Fatty Acid Catabolic Process Cellular Localization Negative Regulation Of Protein Oligomerization Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Linoleic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Protein Import Into Peroxisome Matrix Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Brain Development Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Head Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Membrane Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Protein Transport Substantia Nigra Development Cellular Lipid Metabolic Process Central Nervous System Development Long-chain Fatty Acid Transport Endoplasmic Reticulum Organization Carboxylic Acid Metabolic Process Positive Regulation Of Multicellular Organism Growth Intracellular Protein Transmembrane Transport	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		absent adds biomarkers breastfed breastfeeding confer cpt1a discriminate distinguish dyslipidaemia dyslipidaemic fasn fed formula homa idefics indicative infant insr lepr lifestyle mentioned metabolic overweight pbc pbcs pparalpha transcript triglyceride	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		absent adds biomarkers breastfed breastfeeding confer cpt1a discriminate distinguish dyslipidaemia dyslipidaemic fasn fed formula homa idefics indicative infant insr lepr lifestyle mentioned metabolic overweight pbc pbcs pparalpha transcript triglyceride	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?