C11orf58 and MBTPS1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		C11orf58	MBTPS1
Gene Name		chromosome 11 open reading frame 58	membrane-bound transcription factor peptidase, site 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Golgi Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Integral Component Of Membrane
	Molecular Function	Molecular_function	Serine-type Endopeptidase Activity
	Biological Process	Biological_process	Proteolysis Lipid Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Lysosome Organization Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Response To Endoplasmic Reticulum Stress Regulation Of Transcription Factor Import Into Nucleus Cellular Protein Metabolic Process Small Molecule Metabolic Process
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) Metabolism of lipids and lipoproteins ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: A2M EEF1G FBN3 KIAA1377 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48	10 interactors: ATF6B BDNF BIRC3 C11orf58 CANX CDK2AP2 SPHK1 TNFRSF14 TNFSF11 ZBED8
Entrez ID		10944	8720
HPRD ID		18069	04522
Ensembl ID			ENSG00000140943
Uniprot IDs		O00193	Q14703
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity RNA Splicing Negative Regulation Of Complement Activation, Lectin Pathway Endoplasmic Reticulum Unfolded Protein Response	Positive Regulation Of Protein Modification Process Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Cytokine Positive Regulation Of Protein Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of Secretion Cellular Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Regulation Of Protein Phosphorylation Signaling Regulation Of Protein Metabolic Process Cell Communication Response To Anesthetic Positive Regulation Of Corticotropin-releasing Hormone Secretion Response To Fluoxetine Response To L-glutamate Sphingoid Catabolic Process Positive Regulation Of Cell Development Response To Organic Substance Defense Response Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling TNFSF11-mediated Signaling Pathway Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Ubiquitination Regulation Of Secretion Taste Bud Development Dendrite Extension Cellular Response To Norepinephrine Stimulus Regulation Of Retinal Cell Programmed Cell Death Positive Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Osteoclast Development Positive Regulation Of Transport Cell Surface Receptor Signaling Pathway Osteoclast Proliferation Axon Target Recognition Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?