RNPS1 and U2AF1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		RNPS1	U2AF1
Gene Name		RNA binding protein S1, serine-rich domain	U2 small nuclear RNA auxiliary factor 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding RS Domain Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: ACIN1 CHERP CLK2 DVL2 HEXIM2 HOXD4 LUC7L3 NKTR PIN1 PNN PRPF38A RBM8A SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRSF1 SRSF11 SRSF4 SRSF6 TAF2 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 YWHAB YWHAG ZBTB14 ZNF473 ZNF490	38 interactors: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRPK2 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2
Entrez ID		10921	7307
HPRD ID		07341	01871
Ensembl ID		ENSG00000205937	ENSG00000160201
Uniprot IDs		D3DU92 Q15287	Q01081 Q7Z780
PDB IDs		4A8X	1JMT
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Splicing RNA Processing Gene Expression Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA 3'-end Processing Nuclear Export MRNA Transport Nitrogen Compound Metabolic Process RNA Transport RNA Localization Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleocytoplasmic Transport Nuclear Transport Transcription, DNA-templated RNA Biosynthetic Process Cytoplasmic Transport Intracellular Transport Regulation Of Gene Expression Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Establishment Of Localization In Cell Cellular Localization Macromolecule Biosynthetic Process Regulation Of Metabolic Process MRNA Splice Site Selection Metabolic Process Ribonucleoprotein Complex Biogenesis	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus RNA Export From Nucleus MRNA 3'-end Processing Termination Of RNA Polymerase II Transcription RNA 3'-end Processing MRNA Transport Nuclear Export RNA Transport RNA Localization DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Nucleocytoplasmic Transport Nuclear Transport Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Process Regulation Of Gene Expression Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Viral Process Transcription From RNA Polymerase II Promoter Intracellular Transport Cellular Macromolecular Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Cellular Localization Negative Regulation Of RNA Splicing Negative Regulation Of Gene Expression Positive Regulation Of Viral Genome Replication Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		acinus bcl constructs corepressor demonstrates driven enhances explored inc isoforms manner minigene periodicals physiol promoters ra rar rarbeta repressed responsive retinoic rrm splice splicing stimulates varying weak weaker wiley	allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternal maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency
Tagcloud (Difference) ?		acinus bcl constructs corepressor demonstrates driven enhances explored inc isoforms manner minigene periodicals physiol promoters ra rar rarbeta repressed responsive retinoic rrm splice splicing stimulates varying weak weaker wiley	allelic arisen biallelic biallellic chimeric chimerism compromised developmentally es establishes fetal fetuses h19 igf2 igf2r imprinted interstitial mandible manipulation maternal maternally paternally persist persisted polyhydramnios preimplantation repression rs1 totipotency
Tagcloud (Intersection) ?