ARIH2 and UBE2R2

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		ARIH2	UBE2R2
Gene Name		ariadne RBR E3 ubiquitin protein ligase 2	ubiquitin-conjugating enzyme E2R 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm
	Molecular Function	Nucleic Acid Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Multicellular Organismal Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Developmental Cell Growth Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Hematopoietic Stem Cell Proliferation	Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		44 interactors: ARAP1 BUB1 CBR3 CCDC33 CUL5 DISC1 DLST EEF1A1 EEF1G EML4 ENSA IL4R KAT5 KCNQ2 KIAA1377 LOC147791 NEDD8 PHF7 PPP2R1A PTN REL RHEB RPL8 SCAMP2 SGCE SLC1A6 TP53 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2L6 UBE2N UBE2R2 UBE2T UBE2V1 UGP2 UTP14A WDR91	17 interactors: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 DTX3L DZIP3 FBXW5 INF2 MEOX1 PNPLA2 RBX1 RNF113B UBA1 UBC
Entrez ID		10425	54926
HPRD ID		09286	15602
Ensembl ID		ENSG00000177479	ENSG00000107341
Uniprot IDs		O95376 Q6IBL8	Q712K3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process ISG15-protein Conjugation Catabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Toll-like Receptor 4 Signaling Pathway Protein Monoubiquitination Cell Cycle Toll-like Receptor Signaling Pathway Mitotic Cell Cycle Process Pattern Recognition Receptor Signaling Pathway Mitotic Cell Cycle Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Cellular Response To Organic Substance Response To Organic Substance Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Positive Regulation Of Innate Immune Response Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stimulus Response To Stimulus Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Proteolysis Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Mitotic Spindle Assembly Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Immune Response Regulation Of Cell Cycle Phase Transition	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of ERBB Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Wnt Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Wnt Signaling Pathway Rhythmic Process
Tagcloud ?		aldo1 anxa2 cdna cerebral characterize coding cortical ddit3 egr1 endoplasmic ero1l fold gadd153 gas5 giig11 gpi1 hig1 hypoxia microarray ndr1 neuronal p4hb profiling reinforce repressed reticulum sac1p ubiquitination vdac2
Tagcloud (Difference) ?		aldo1 anxa2 cdna cerebral characterize coding cortical ddit3 egr1 endoplasmic ero1l fold gadd153 gas5 giig11 gpi1 hig1 hypoxia microarray ndr1 neuronal p4hb profiling reinforce repressed reticulum sac1p ubiquitination vdac2
Tagcloud (Intersection) ?