UBE2R2 and DZIP3

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2R2	DZIP3
Gene Name		ubiquitin-conjugating enzyme E2R 2	DAZ interacting zinc finger protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Phosphatase Binding Polyubiquitin Binding Poly(A) RNA Binding
	Biological Process	Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Protein Polyubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 DTX3L DZIP3 FBXW5 INF2 MEOX1 PNPLA2 RBX1 RNF113B UBA1 UBC	42 interactors: AKTIP AP1M1 ARHGAP32 ATXN1 BIRC2 BIRC3 CEP63 DAZ1 GTF2H2C_2 HNRNPF HNRNPUL1 HOTAIR NCOR1 PCGF3 RAD18 RBM4B RNF38 TOLLIP TRIM21 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765
Entrez ID		54926	9666
HPRD ID		15602	10562
Ensembl ID		ENSG00000107341	ENSG00000198919
Uniprot IDs		Q712K3	Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of ERBB Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Wnt Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Wnt Signaling Pathway Rhythmic Process	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Activation Of Innate Immune Response Cellular Metabolic Process Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Protein Monoubiquitination Proteolysis Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Ubiquitination DNA Repair Regulation Of Metabolic Process Innate Immune Response Immune Response-regulating Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Stress Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Postreplication Repair Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Process
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