TNIP1 and TTF2

Number of citations of the paper that reports this interaction (PMID 12927788)
7

Data Source:
HPRD (two hybrid)

		TNIP1	TTF2
Gene Name		TNFAIP3 interacting protein 1	transcription termination factor, RNA polymerase II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Spliceosomal Complex Cytoplasm Transcription Elongation Factor Complex
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding	DNA Binding Protein Binding ATP Binding ATP-dependent Helicase Activity DNA-dependent ATPase Activity Zinc Ion Binding
	Biological Process	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)
Protein-Protein Interactions		61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1	22 interactors: CDC5L CDKL3 CLPB DCP1A DR1 DRAP1 HINFP HNRNPA1 HNRNPA2B1 KIF4A MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TNIP1 ZSCAN1
Entrez ID		10318	8458
HPRD ID		09216	05280
Ensembl ID		ENSG00000145901
Uniprot IDs		A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025	Q9UNY4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus	Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Heterocycle Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cell Cycle Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cellular Metabolic Process Mitotic Spindle Assembly Regulation Of Nitrogen Compound Metabolic Process Spindle Organization Negative Regulation Of Cellular Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Dendrite Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Transcription, DNA-templated Regulation Of Cell Morphogenesis Biosynthetic Process Mitotic Spindle Organization Positive Regulation Of Neuron Projection Development MRNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Male Germ Cell Proliferation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Stress RNA Splicing, Via Transesterification Reactions Positive Regulation Of Dendrite Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing	away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates localize nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2
Tagcloud (Difference) ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing	away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates localize nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2
Tagcloud (Intersection) ?