TNIP1 and MAGEB18

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		TNIP1	MAGEB18
Gene Name		TNFAIP3 interacting protein 1	melanoma antigen family B, 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Cytoplasm
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding	Protein Binding
	Biological Process	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)	Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1	8 interactors: ATXN1 CTAGE5 GABPB1 HTT LNX1 TNIP1 TP53 TRIM37
Entrez ID		10318	286514
HPRD ID		09216	06647
Ensembl ID		ENSG00000145901	ENSG00000176774
Uniprot IDs		A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025	Q96M61
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus	Determination Of Adult Lifespan Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Gene Expression Regulation Of Membrane Permeability Nucleocytoplasmic Transport Multicellular Organismal Aging Nuclear Transport Negative Regulation Of Neural Precursor Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter Neuron Apoptotic Process Response To Light Stimulus Mitochondrial Membrane Organization Visual Learning Positive Regulation Of Metabolic Process Neuron Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Visual Behavior Mitochondrion Organization Cell Aging Negative Regulation Of Signal Transduction Protein Oligomerization Associative Learning Neural Plate Formation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Radiation Negative Regulation Of Signaling Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Macromitophagy Serotonin Uptake Oligodendrocyte Apoptotic Process Lactate Biosynthetic Process From Pyruvate Protein Import Into Nucleus Nuclear Import Behavior Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Learning Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Helicase Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Phosphatase Type 2A Activity Histone H2A-K119 Monoubiquitination Mitochondrial Transport Protein Import Positive Regulation Of Cellular Biosynthetic Process Cytoplasmic Transport Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Protein Localization To Nucleus
Tagcloud ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Difference) ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Intersection) ?