TNIP1 and VPS33B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TNIP1	VPS33B
Gene Name		TNFAIP3 interacting protein 1	vacuolar protein sorting 33 homolog B (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Cytoplasm Lysosome Lysosomal Membrane Late Endosome HOPS Complex Platelet Alpha Granule Late Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding	Protein Binding
	Biological Process	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade	Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Melanosome Localization Lysosome Localization Membrane Fusion Platelet Alpha Granule Organization
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)
Protein-Protein Interactions		61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1	6 interactors: APP MAPK8IP2 TNIP1 UVRAG VIPAS39 ZAK
Entrez ID		10318	26276
HPRD ID		09216	10541
Ensembl ID		ENSG00000145901	ENSG00000184056
Uniprot IDs		A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025	B3KQF6 F5H008 Q9H267
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus	Mating Behavior Mating Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation JNK Cascade Regulation Of Phosphorus Metabolic Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Interaction With Host Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Stress Stress-activated MAPK Cascade Regulation Of Receptor Activity Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Synaptic Growth At Neuromuscular Junction Learning Dendrite Development Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Sexual Reproduction Regulation Of JNK Cascade Collateral Sprouting In Absence Of Injury Regulation Of Stress-activated MAPK Cascade Regulation Of Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Nonassociative Learning MAPK Cascade Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Reproduction Regulation Of Protein Phosphorylation Axon Choice Point Recognition Learning Or Memory Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation SNARE Complex Assembly Cognition Neuron Remodeling Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Cellular Protein Complex Assembly Reproductive Process Defense Response Regulation Of Signaling Signal Complex Assembly Cellular Response To Stress Positive Regulation Of Catalytic Activity Cellular Copper Ion Homeostasis
Tagcloud ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing	acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Difference) ?		1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing	acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Intersection) ?