ERCC5

Gene Name		excision repair cross-complementation group 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor A Complex Holo TFIIH Complex DNA-directed RNA Polymerase II, Holoenzyme Intermediate Filament Cytoskeleton
	Molecular Function	Bubble DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Endonuclease Activity Endodeoxyribonuclease Activity Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein N-terminus Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Removal DNA Catabolic Process, Endonucleolytic DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Response To UV UV Protection Response To UV-C Negative Regulation Of Apoptotic Process
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Transcription-coupled NER (TC-NER) Formation of incision complex in GG-NER Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in GG-NER Dual incision reaction in TC-NER
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: ERCC2 ERCC6 EWSR1 GTF2H1 GTF2H4 NTHL1 PCNA POLR2A
Entrez ID		2073
HPRD ID		00595
Ensembl ID		ENSG00000134899
Uniprot IDs		P28715
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair DNA-templated Transcription, Elongation DNA Repair Transcription Elongation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Cellular Response To DNA Damage Stimulus Positive Regulation Of Viral Transcription DNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Nucleotide-excision Repair, DNA Damage Removal Cellular Response To Stress Termination Of RNA Polymerase I Transcription DNA Catabolic Process Transcription Initiation From RNA Polymerase I Promoter Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Base-excision Repair DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Nucleotide-excision Repair, DNA Incision Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process MRNA Processing Aromatic Compound Catabolic Process Nitrogen Compound Metabolic Process Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA Metabolic Process Viral Process Transcription, DNA-templated RNA Processing RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression
Tagcloud ?		bisphenol bodies bpa characterize collectively cysteine differentially disruptor electrochemical endocrine endonuclease etc excision experiment focused harmful hek293 impacts implied list mcf microscopic morphology notably observation profiling repair seq