APP |
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
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- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Phenserine
- Tiomolibdate ion
- CAD106
- Mito-4509
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
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APPL2 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 |
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CCR10 |
C-C motif chemokine receptor 10 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
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DGKI |
diacylglycerol kinase iota |
- Effects of PIP2 hydrolysis
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EEA1 |
early endosome antigen 1 |
- Toll Like Receptor 9 (TLR9) Cascade
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- Inositol 1,3-Bisphosphate
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GLP1R |
glucagon like peptide 1 receptor |
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- G alpha (s) signalling events
- Glucagon-type ligand receptors
- ADORA2B mediated anti-inflammatory cytokines production
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- Glucagon recombinant
- Exenatide
- Liraglutide
- Albiglutide
- Dulaglutide
- Lixisenatide
- Semaglutide
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HOXB13 |
homeobox B13 |
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HRAS |
HRas proto-oncogene, GTPase |
- SOS-mediated signalling
- Activation of RAS in B cells
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- SHC1 events in ERBB2 signaling
- SHC1 events in ERBB4 signaling
- Signaling by SCF-KIT
- Signalling to RAS
- p38MAPK events
- p38MAPK events
- GRB2 events in EGFR signaling
- SHC1 events in EGFR signaling
- Downstream signal transduction
- GRB2 events in ERBB2 signaling
- GRB2 events in ERBB2 signaling
- Tie2 Signaling
- EGFR Transactivation by Gastrin
- DAP12 signaling
- SHC-related events triggered by IGF1R
- FCERI mediated MAPK activation
- NCAM signaling for neurite out-growth
- EPHB-mediated forward signaling
- Ras activation upon Ca2+ influx through NMDA receptor
- VEGFR2 mediated cell proliferation
- CD209 (DC-SIGN) signaling
- Constitutive Signaling by EGFRvIII
- SHC-mediated cascade:FGFR1
- FRS-mediated FGFR1 signaling
- SHC-mediated cascade:FGFR2
- FRS-mediated FGFR2 signaling
- SHC-mediated cascade:FGFR3
- FRS-mediated FGFR3 signaling
- FRS-mediated FGFR4 signaling
- SHC-mediated cascade:FGFR4
- Signaling by FGFR2 in disease
- Signaling by FGFR4 in disease
- Signaling by FGFR1 in disease
- Regulation of RAS by GAPs
- RAF activation
- RAF/MAP kinase cascade
- MAP2K and MAPK activation
- Negative regulation of MAPK pathway
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF fusions
- RAS signaling downstream of NF1 loss-of-function variants
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Insulin receptor signalling cascade
- PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
- MET activates RAS signaling
- Signaling by FGFR3 fusions in cancer
- Signaling by FGFR3 point mutants in cancer
- Activated NTRK2 signals through RAS
- Erythropoietin activates RAS
- Activated NTRK2 signals through FRS2 and FRS3
- Activated NTRK3 signals through RAS
- FLT3 Signaling
- Constitutive Signaling by Overexpressed ERBB2
- Estrogen-stimulated signaling through PRKCZ
- RAS GTPase cycle mutants
- Signaling downstream of RAS mutants
- Signaling by ERBB2 KD Mutants
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
- Signaling by PDGFRA extracellular domain mutants
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- Hexane-1,6-Diol
- Trifluoroethanol
- Guanosine-5'-Triphosphate
- Guanosine-5'-Diphosphate
- N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE
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- Bladder cancer
- Penile cancer
- Squamous cell carcinoma
- Thyroid cancer
- Cervical cancer
- Hepatocellular carcinoma
- Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
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INCA1 |
inhibitor of CDK, cyclin A1 interacting protein 1 |
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KRT15 |
keratin 15 |
- Keratinization
- Formation of the cornified envelope
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RABAC1 |
Rab acceptor 1 |
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RAPGEFL1 |
Rap guanine nucleotide exchange factor like 1 |
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RBSN |
rabenosyn, RAB effector |
- Toll Like Receptor 9 (TLR9) Cascade
- Factors involved in megakaryocyte development and platelet production
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RIN2 |
Ras and Rab interactor 2 |
- RAB GEFs exchange GTP for GDP on RABs
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- Macrocephaly, alopecia, cutis laxa, and scoliosis; MACS syndrome
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RIN3 |
Ras and Rab interactor 3 |
- RAB GEFs exchange GTP for GDP on RABs
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SGSM3 |
small G protein signaling modulator 3 |
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SLC27A2 |
solute carrier family 27 member 2 |
- Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
- Synthesis of bile acids and bile salts via 24-hydroxycholesterol
- Alpha-oxidation of phytanate
- Neutrophil degranulation
- Peroxisomal protein import
- Peroxisomal protein import
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TBC1D15 |
TBC1 domain family member 15 |
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TBC1D17 |
TBC1 domain family member 17 |
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