| APP |
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
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- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Phenserine
- Tiomolibdate ion
- CAD106
- Mito-4509
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
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| FAF1 |
Fas associated factor 1 |
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| GJB2 |
gap junction protein beta 2 |
- Oligomerization of connexins into connexons
- Transport of connexins along the secretory pathway
- Gap junction assembly
- Transport of connexons to the plasma membrane
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- Keratitis-ichthyosis-deafness syndrome
- Palmoplantar keratoderma with deafness
- Deafness, autosomal dominant
- Deafness, autosomal recessive
- Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
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| GRM7 |
glutamate metabotropic receptor 7 |
- G alpha (i) signalling events
- Class C/3 (Metabotropic glutamate/pheromone receptors)
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| GUCD1 |
guanylyl cyclase domain containing 1 |
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| LIMD1 |
LIM domains containing 1 |
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
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| MAP3K2 |
mitogen-activated protein kinase kinase kinase 2 |
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| NSFL1C |
NSFL1 cofactor |
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| OPA3 |
outer mitochondrial membrane lipid metabolism regulator OPA3 |
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- 3-Methylglutaconic aciduria (MGCA)
- Autosomal dominant optic atrophy (DOA); Kjer's optic neuropathy
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| PROC |
protein C, inactivator of coagulation factors Va and VIIIa |
- Intrinsic Pathway of Fibrin Clot Formation
- Common Pathway of Fibrin Clot Formation
- Gamma-carboxylation of protein precursors
- Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
- Removal of aminoterminal propeptides from gamma-carboxylated proteins
- Cell surface interactions at the vascular wall
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
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- Menadione
- Sodium Tetradecyl Sulfate
- Cupric Chloride
- Protein S human
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| RAD23A |
RAD23 homolog A, nucleotide excision repair protein |
- Josephin domain DUBs
- DNA Damage Recognition in GG-NER
- Formation of Incision Complex in GG-NER
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| RAD23B |
RAD23 homolog B, nucleotide excision repair protein |
- N-glycan trimming in the ER and Calnexin/Calreticulin cycle
- Josephin domain DUBs
- DNA Damage Recognition in GG-NER
- Formation of Incision Complex in GG-NER
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| SH3BP1 |
SH3 domain binding protein 1 |
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| SRPK2 |
SRSF protein kinase 2 |
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- Adenine
- Purvalanol
- Phosphoaminophosphonic Acid-Adenylate Ester
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| TRAFD1 |
TRAF-type zinc finger domain containing 1 |
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| TRIM54 |
tripartite motif containing 54 |
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| UBQLN1 |
ubiquilin 1 |
- Cargo recognition for clathrin-mediated endocytosis
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| UBXN2B |
UBX domain protein 2B |
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| VCP |
valosin containing protein |
- Translesion Synthesis by POLH
- HSF1 activation
- ABC-family proteins mediated transport
- N-glycan trimming in the ER and Calnexin/Calreticulin cycle
- Hedgehog ligand biogenesis
- Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
- Defective CFTR causes cystic fibrosis
- Josephin domain DUBs
- Ovarian tumor domain proteases
- Neutrophil degranulation
- E3 ubiquitin ligases ubiquitinate target proteins
- Protein methylation
- Aggrephagy
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- Phosphoaminophosphonic Acid-Adenylate Ester
- Phenethyl Isothiocyanate
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- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
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