CDC5L and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		CDC5L	EXOC1
Description		cell division cycle 5 like	exocyst complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Cytoplasm Membrane Nuclear Speck Perinuclear Region Of Cytoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Protein Phosphatase 1 Binding Protein Kinase Binding Leucine Zipper Domain Binding WD40-repeat Domain Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTP-Rho Binding
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome DNA Repair Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Interleukin-2 Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Wortmannin Cellular Response To Nerve Growth Factor Stimulus Cellular Response To Prolactin	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Exocyst Localization Defense Response To Virus
Pathways		mRNA Splicing - Major Pathway	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Chin dimples ( 27182965) FEV1 ( 30804560) Height ( 28552196) Ischemic stroke ( 26089329) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Stroke (ischemic) ( 22941190)	Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		69 interacting genes: AKAP6 AKAP9 BCAS2 BICRAL CALM1 CCDC136 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANSL1 KDM1A KIF3C KIF5B KRT18 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 TRAF3IP1 TRAK1 TRIO TTF2 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZSCAN1	27 interacting genes: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		988	55763
HPRD ID		04184	07615
Ensembl ID		ENSG00000096401	ENSG00000090989
Uniprot IDs		Q99459	A0A024RDA1 A1LT29 Q9NV70
PDB IDs		2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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