EXOC1 and RUBCN

Number of citations of the paper that reports this interaction (PubMedID 21241894)
123

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EXOC1	RUBCN
Description		exocyst complex component 1	rubicon autophagy regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTP-Rho Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Exocyst Localization Defense Response To Virus	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		27 interacting genes: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	2 interacting genes: EXOC1 SMAD9
Entrez ID		55763	9711
HPRD ID		07615	11069
Ensembl ID		ENSG00000090989	ENSG00000145016
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	Q8N4U6 Q92622
PDB IDs
Enriched GO Terms of Interacting Partners?
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