BAG4 and RNF20

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BAG4	RNF20
Description		BAG cochaperone 4	ring finger protein 20
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus HULC Complex
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	P53 Binding Chromatin Binding Transcription Coactivator Activity MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Metal Ion Binding
	Biological Process	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Negative Regulation Of Cell Migration Positive Regulation Of Histone Methylation Histone H2B Ubiquitination Positive Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Histone H2B Ubiquitination
Pathways		Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25	30 interacting genes: AMOTL2 ATM BAG4 FBXO7 FGFR4 H2AC18 H2AC20 H2BC21 H2BC3 H3C14 H4C14 HSF1 HTT ITSN2 KIF11 MSL1 PA2G4 PAF1 RB1CC1 RNF40 SMURF2 TRIM14 UBE2A UBE2B UBE2D2 UBE2E1 UBE2L3 USHBP1 XRCC3 ZDHHC17
Entrez ID		9530	56254
HPRD ID		04861	07410
Ensembl ID		ENSG00000156735	ENSG00000155827
Uniprot IDs		O95429	Q5VTR2
PDB IDs		1M62 1M7K	5TRB
Enriched GO Terms of Interacting Partners?
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